Search for dissertations about: "Nerve Regeneration: physiology"

Showing result 1 - 5 of 7 swedish dissertations containing the words Nerve Regeneration: physiology.

2. 1. Studies on Peripheral Nerve Regeneration: Microdispensing, Neurite Guidance and Galectins

   Author : Per Gustavsson; Funktionell zoologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; vävnadskultur; histokemi; cytokemi; Histologi; tissue culture; histochemistry; cytochemistry; Histology; Schwann cells; sciatic nerve; dorsal root ganglia; DRG; neurite guidance; galectins; inkjet; microdispensing; peripheral nervous system; nerve regeneration; Animal physiology; Djurfysiologi; Biotechnology; Bioteknik;

   Abstract : The present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. READ MORE

4. 2. Vascular Endothelial Growth Factor (VEGF) and Peripheral Nerve Regeneration

   Author : Mariann Sondell; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Schwann cell; SCG; rat; peripheral nerve regeneration; neuropilin-1; nerve repair; mouse; growth factor; flk-1; axonal outgrowth; DRG; VEGF; Animal physiology; Djurfysiologi;

   Abstract : This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. READ MORE

5. 3. Phospholipase A2 in nerve injury and axonal outgrowth

   Author : Marie Hornfelt; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurology; cell death; apoptosis; leukotrienes; arachidonic acid; M-type receptor; secretory phospholipase A2; cytosolic phospholipase A2; sciatic nerve; dorsal root ganglia; growth cone; axonal outgrowth; nerve injury; peripheral nerve regeneration; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; Animal physiology; Djurfysiologi;

   Abstract : This thesis deals with processes coupled to injury in the peripheral nervous system (PNS), with a general aim to investigate the role of phospholipase A2 (PLA2) enzymes in axonal outgrowth. The axonal outgrowth of dorsal root ganglia (DRG) neurons in vitro was reduced by several different inhibitors of PLA2 activity and enhanced by an activator of this enzyme. READ MORE

6. 4. JNK/c-Jun Signaling and Peripheral Nerve Regeneration

   Author : Charlotta Lindwall; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; neuropsykologi; neurofysiologi; neurophysiology; Neurologi; neuropsychology; Neurology; Djurfysiologi; Animal physiology; JNK; signal transduction; nerve regeneration;

   Abstract : The events associated with axonal injury in the peripheral nervous system (PNS) have been described in detail. However, the molecular mechanisms underlying the regenerative response, or neuronal cell death, following axonal injury are poorly understood. READ MORE

7. 5. Macrophages, Nitric oxide synthases and Heme oxygenases: possible roles during peripheral nerve regeneration

   Author : Sofia Magnusson; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; satellite cells; peripheral ganglia; cell signalling; nerve regeneration; heme oxygenase; Macrophages; nitric oxide synthase; Animal physiology; Djurfysiologi;

   Abstract : The purpose of this study was to investigate the suggestions that macrophages, and the systems generating nitric oxide (NO) and carbon monoxide (CO), i.e. nitric oxide synthases (NOS) and heme oxygenases (HO), could be important for peripheral nerve regeneration. READ MORE