Search for dissertations about: "Neu5Ac"
Showing result 1 - 5 of 6 swedish dissertations containing the word Neu5Ac.
-
1. Tailored conjugates of N-acetylneuraminic acid and small molecules that block virus cell attachment and entry
Abstract : Viruses are obligate intracellular parasites, unable to replicate without exploiting machinery andmaterials from host cells. Pandemics of viral diseases have had large impacts on human socieities and are continued threats to global health. READ MORE
-
2. Some New Methods in Sialic Acid Chemistry
Abstract : Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. READ MORE
-
3. Sialic acid-dependent binding specificities of Helicobacter pylori and influenza virus. Importance of different parts of the binding sequences
Abstract : Many viruses and bacteria adhere to host cell glycoconjugates in a specific manner, utilizing selected carbohydrate sequences. The aim of this work was to investigate at a molecular level the interactions of two important human pathogens, influenza virus and Helicobacter pylori, with sialylated carbohydrate structures. READ MORE
-
4. Glycan-based interactions of Streptococcus pneumoniae and the host
Abstract : Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or meningitis. Pneumococci spread via aerosols. READ MORE
-
5. Structural studies on lipopolysaccharides from haemophilus species
Abstract : Background: Carbohydrates are indispensable mediators for a variety of cellular interactions. In biological systems carbohydrates are usually linked to a carrier as e.g. proteins or lipids. READ MORE
