Search for dissertations about: "Neural Crest Stem Cells"
Showing result 11 - 15 of 26 swedish dissertations containing the words Neural Crest Stem Cells.
-
11. Novel skeletal stem and progenitor cells and their regulation
Abstract : The development of bone and cartilage, which provide the framework of the skeletal system, is complex. In this context stem and progenitor cells play a crucial role by producing differentiated cells. Hormones are important regulators of this process, with growth hormone (GH) acting as the major endocrine regulator of longitudinal bone growth. READ MORE
-
12. Hypoxia and Stem Cells in Normal and Tumor Development
Abstract : Neuroblastoma is a childhood malignancy of the sympathetic nervous system and accounts for 15% of all cancer-related deaths in children. To understand the biology behind neuroblastoma, clarify timing of cellular events and expression profiles of proteins preceding neuroblastoma initiation, we need more relevant preclinical models. READ MORE
-
13. Functional studies of two forkhead genes
Abstract : Forkhead genes are functionally diverse and several have been linked to human disease. A previous screen for forkhead genes identified the family member FOXS1. To characterize the function of this gene, we produced a mouse model in which the Foxs1 gene was replaced by a lacZ marker allele. READ MORE
-
14. Reconnecting the CNS and PNS with Stem Cell Transplantation
Abstract : Severe injury may result in disconnection between the peripheral and central nervous system. Regeneration of the central portion of sensory neurons into the spinal cord is notoriously poor in adult mammals, with low regenerative drive and an unpermissive central environment, most likely resulting in persistent loss of sensory function. READ MORE
-
15. Developing new models of childhood malignancies using human induced pluripotent stem cells
Abstract : Early onset diseases such as childhood malignancies and neurodevelopmental disorders have been intricate to study. For many years, research has relied and dependent upon different animal systems. READ MORE