Search for dissertations about: "Neurochemistry and Molecular Neurobiology"

Showing result 1 - 5 of 71 swedish dissertations containing the words Neurochemistry and Molecular Neurobiology.

  1. 1. Cell-penetrating peptides in protein mimicry and oligonucleotide delivery Applications and mechanisms

    University dissertation from Stockholm : Institutionen för neurokemi

    Author : Henrik Johansson; Stockholms universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peptide; oligonucleotide; cell-penetrating peptide; PNA; splicing; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : The plasma membrane functions as a barrier, restricting entry of hydrophilic pharmaceutical agents. Cell-penetrating peptides (CPPs) are capable of transporting bioactive cargos into the cell and have consequently been extensively investigated for their mechanism of entry and capability to deliver various cargos spanning from peptides to plasmids. READ MORE

  2. 2. Identification and characterization of nuclear envelope protein interactions

    University dissertation from Stockholm : Department of Neurochemistry, Stockholm University

    Author : Balaje Vijayaraghavan; Stockholms universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Samp1; MCLIP; Nuclear envelope; Ran; Emerin; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The Nuclear envelope which surrounds the chromatin of eukaryotic cells contains more than a hundred transmembrane proteins. Mutations in some genes encoding nuclear envelope proteins give rise to human diseases including neurological disorders. The function of many nuclear envelope proteins is not well established. READ MORE

  3. 3. Gene therapy tools: oligonucleotides and peptides

    University dissertation from Stockholm : Department of Neurochemistry, Stockholm University

    Author : Jonas Eriksson; Stockholms universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gene therapy; oligonucleotide; peptide; RNA-cleaving deoxyribozyme; deoxyribozyme; DNAzyme; cell-penetrating peptide; CPP; enzyme; enzyme kinetics; kinetic assay; assay; telomerase; telomerase inhibitor; imetelstat; GRN163L; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Genetic mutations can cause a wide range of diseases, e.g. cancer. Gene therapy has the potential to alleviate or even cure these diseases. READ MORE

  4. 4. Cell-penetrating peptides as delivery vectors for oligonucleotides and proteins Studies on applications and toxicity

    University dissertation from Stockholm : Institutionen för neurokemi

    Author : Peter Järver; Stockholms universitet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Cell-penetrating peptides (CPPs) have for a little bit more than a decade been employed as delivery vectors for a wide range of cargoes, ranging from gold particles to entire plasmids. Although CPP are well studied and utilized in numerous publications, our knowledge about CPP mediated transport is still poor. READ MORE

  5. 5. Studies on Human and Drosophila melanogaster Glutathione Transferases of Biomedical and Biotechnological Interest

    University dissertation from Stockholm : Department of Neurochemistry, Stockholm University

    Author : Aslam M.A. Mazari; Stockholms universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; glutathione transferases; detoxication; hpgds inhibition; immobilization; isothiocyanates; drosophila GSTs; environmental pollutants; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Glutathione transferases (GSTs, EC.2.5.1. READ MORE