Search for dissertations about: "Neurochemistry and Neurotoxicology"

Showing result 1 - 5 of 24 swedish dissertations containing the words Neurochemistry and Neurotoxicology.

  1. 1. Galanin and neuropeptide Y analogs : receptor-ligand interactions and pharmacology

    University dissertation from Stockholm : Stockholm University

    Author : Ulrika Kahl; Stockholms universitet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : .... READ MORE

  2. 2. Temporal events in neuronal differentiation and cell death : expression and processing of the Alzheimer's amyloid precursor protein family and a protein at the nuclear pore

    University dissertation from Stockholm : Dep. of Neurochemistry, Stockholm University

    Author : Marie Beckman; Stockholms universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : The present study had two major objectives: 1) to elucidate the involvement of Alzheimer’s amyloid precursor protein (APP) family in neuronal differentiation, and the effect of the Alzheimer’s disease (AD)-linked mutation APPV642I on signal transduction; 2) to investigate the fate of the nuclear pore complex protein POM121 during apoptosis and to examine the possibility of using green fluorescent protein (GFP)-labelled POM121 as a non-invasive sensor of apoptosis in living (non-fixed) cells.APP is the parent protein of the b-amyloid peptide, which is the major peptide constituent in the “senile plaques” of AD. READ MORE

  3. 3. Up-regulation of dopamine D₂ receptors : in vitro and in vivo studies

    University dissertation from Stockholm : Stockholms universitet

    Author : Maria Wanderoy; Stockholms universitet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : In the central nervous system (CNS) dopaminergic and dopaminoceptive neurons have the ability to respond to variations in dopamine levels by for example adjusting their dopamine receptor levels. One of the most well known phenomena in this respect is that long-term blockade of D2 receptors with antipsychotic drugs leads to an increase in striatal D2 receptor density of experimental animals as well as of schizophrenic patients as measured in both post-mortem studies and in vivo positron emission tomography studies of brain. READ MORE

  4. 4. On inflammatory cytokines and β-amyloid peptides in acute and chronic neurodegeneration

    University dissertation from Stockholm : Department of Neurochemistry and Neurotoxicology, Stockholm University

    Author : Roya Tehranian; Stockholms universitet.; [2001]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; Cytokines; Amyloid; Peptides; Nerve degeneration; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : Insults to the brain as well as neurodegenerative diseases are known to elicit inflammatory responses. Inflammation in the brain can on one hand initiate processes that are harmful to the injured tissue and exacerbate the damage, leading to neuronal degeneration and glial activation, and on the other hand activate processes that may be necessary for repair mechanisms and regeneration. READ MORE

  5. 5. Design and evaluation of drug delivery vehicles

    University dissertation from Stockholm : Institutionen för neurokemi

    Author : Caroline Palm Apergi; Stockholms universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : A crucial aspect of drug delivery is efficient transport to the site of action. Thus, there is a need to design and evaluate new delivery vehicles. In this thesis two delivery vehicles, cell-penetrating peptides and bacterial ghosts, were evaluated. READ MORE