Search for dissertations about: "Neurochemistry and Neurotoxicology"

Showing result 21 - 22 of 22 swedish dissertations containing the words Neurochemistry and Neurotoxicology.

  2. 21. Astroglial Cells : Role in Neurodegenerative-Inflammatory Processes in the Central Nervous System

    Author : Gun Eriksson; Karl Åkerman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : Inflammatory processes, mediated by the pro-inflammatory cytokines interleukin (IL) -1a/b, tumor necrosis factora(TNFa), IL-6 and excitotoxic actions of glutamate, are proposed to be implicated in neurodegenerative diseases, such as Alzheimer's disease.A neurotoxic fragment ofb-amyloid,bA25-35, was shown to induce a reactive phenotype of primary astrocytes and microglial cells in a time-dependent manner. READ MORE

  4. 22. On Fever Mechanisms & Preoptic Signalling

    Author : Anna Sundgren Andersson; Robert Dantzer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : Fever, a 1-4 °C elevation of the body temperature, is part of the systemic inflammatory response to infection or tissue damage, and it is believed to be a potent host defence. The underlying physiological mechanisms of the febrile response are one of the two main objectives in this thesis, where studies conducted in whole animals (rats and mice), chiefly aimed at clarifying the cytokine cascade in fever. READ MORE