Search for dissertations about: "Neurochemistry and Neurotoxicology"

Showing result 6 - 10 of 24 swedish dissertations containing the words Neurochemistry and Neurotoxicology.

  1. 6. Altered cell signaling linked to neurodegeneration Studies on scrapie-infected neuroblastoma cells and activated microglia 

    University dissertation from Stockholm : Department of Neurochemistry, Stockholm University

    Author : Christina Svensson; Stockholms universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prion disease; Inflammation; MAPK; Microglia activation; Neuroblastoma; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : Prion diseases are neurodegenerative disorders that can affect humans and animals. The underlying event is a conformational change of the normal cellular prion protein (PrPC) into an aberrant isoform termed PrP-scrapie (PrPSc). PrPSc is thought to lead to neurodegeneration and activation of glial cells. READ MORE

  2. 7. Role of interleukin-1 in fever and inflammation

    University dissertation from Stockholm : Institutionen för neurokemi

    Author : Maria Zetterström; Stockholms universitet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : The proinflammatory cytokines interleukin (IL) -1α, IL-1β and IL-6 are key mediators in the host's response to injury and infection. One of the systemic responses elicited by these proinflammatory cytokines, when injected peripherally or centrally, is fever. Thus, these proteins may act as endogenous pyrogens. READ MORE

  3. 8. The Interleukin-1 family of proteins in the brain and adrenal gland : regulation in response to bacterial LPS

    University dissertation from Stockholm : Department of Neurochemistry, Stockholm University

    Author : Susanne Tingsborg; Stockholms universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : Interleukin-1 (IL-1) is mediating diverse physiological conditions as inflammatory response, fever and sickness behaviour but also, via activation of the hypothalamus-pituitary-adrenal (HPA)-axis, the release of the anti-inflammatory adrenocorticoids. The neuroendocrine system as well as the central nervous system (CNS) is involved in the regulation of these conditions in the body. READ MORE

  4. 9. Development of Novel Transport Peptides and Their Application in Antisense Techniques

    University dissertation from Stockholm : Institutionen för neurokemi

    Author : Ursel Soomets; Stockholms universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : .... READ MORE

  5. 10. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells

    University dissertation from Stockholm : Institutionen för neurokemi

    Author : Malin Samuelsson; Stockholms universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; amyloid-β; astrocytes; C EBP; glia; microglia; neuroinflammation; NF-кB; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Abstract : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. READ MORE