Search for dissertations about: "Neurochemistry with Molecular Neurobiology"
Showing result 11 - 15 of 77 swedish dissertations containing the words Neurochemistry with Molecular Neurobiology.
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11. Internalization mechanisms of cell-penetrating peptides : Structure-activity relationships, cellular distribution and membrane toxicity studies
Abstract : Transport of substances with pharmaceutical potential over the plasma membrane has been pushed a great step forward with the discovery of short cationic polypeptides, known as cell-penetrating peptides (CPP). Since then, the internalization mechanism and cargo delivery properties of CPPs has been extensively studied. READ MORE
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12. Chimeric gene delivery vectors : Design, synthesis, and mechanisms from transcriptomics analysis
Abstract : Delivery of nucleic acid is a promising approach for genetic diseases/disorders. However, gene therapy using oligonucleotides (ONs) suffers from low transfection efficacy due to negative charges, weak cellular permeability, and enzymatic degradation. READ MORE
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13. Studies on Human and Drosophila melanogaster Glutathione Transferases of Biomedical and Biotechnological Interest
Abstract : Glutathione transferases (GSTs, EC.2.5.1. READ MORE
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14. Characterization of the inner nuclear membrane protein Samp1, during interphase and mitosis
Abstract : The nucleus, a hallmark in eukaryotic cells, contains the genome separating it from molecules in the cytoplasm. The nucleus is surrounded by a nuclear envelope consisting of two concentric membranes, the outer nuclear membrane and the inner nuclear membrane, the nuclear lamina and nuclear pore complexes. READ MORE
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15. Processing of the amyloid precursor protein and its paralogues amyloid precursor-like proteins 1 and 2
Abstract : Alzheimer’s disease (AD) is a neurodegenerative disorder which is histopathologically characterised by amyloid plaques and neurofibrillary tangles. Amyloid plaques consist of the amyloid β-peptide (Aβ) that can form aggregates in the brain. Aβ is generated from the amyloid precursor protein (APP) through proteolytic cleavage. READ MORE