Search for dissertations about: "Neurochemistry"
Showing result 6 - 10 of 136 swedish dissertations containing the word Neurochemistry.
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6. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells
Abstract : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. READ MORE
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7. Development of Novel Transport Peptides and Their Application in Antisense Techniques
Abstract : .... READ MORE
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8. Altered cell signaling linked to neurodegeneration : Studies on scrapie-infected neuroblastoma cells and activated microglia
Abstract : Prion diseases are neurodegenerative disorders that can affect humans and animals. The underlying event is a conformational change of the normal cellular prion protein (PrPC) into an aberrant isoform termed PrP-scrapie (PrPSc). PrPSc is thought to lead to neurodegeneration and activation of glial cells. READ MORE
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9. The Interleukin-1 family of proteins in the brain and adrenal gland : regulation in response to bacterial LPS
Abstract : Interleukin-1 (IL-1) is mediating diverse physiological conditions as inflammatory response, fever and sickness behaviour but also, via activation of the hypothalamus-pituitary-adrenal (HPA)-axis, the release of the anti-inflammatory adrenocorticoids. The neuroendocrine system as well as the central nervous system (CNS) is involved in the regulation of these conditions in the body. READ MORE
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10. Up-regulation of dopamine D₂ receptors : in vitro and in vivo studies
Abstract : In the central nervous system (CNS) dopaminergic and dopaminoceptive neurons have the ability to respond to variations in dopamine levels by for example adjusting their dopamine receptor levels. One of the most well known phenomena in this respect is that long-term blockade of D2 receptors with antipsychotic drugs leads to an increase in striatal D2 receptor density of experimental animals as well as of schizophrenic patients as measured in both post-mortem studies and in vivo positron emission tomography studies of brain. READ MORE