Search for dissertations about: "Neurodegenerative proteinopathies"
Showing result 1 - 5 of 7 swedish dissertations containing the words Neurodegenerative proteinopathies.
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1. Shining infrared light on amyloid structures in neurodegenerative proteinopathies
Abstract : .... READ MORE
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2. On the nature of mixed neurodegenerative amyloidopathies
Abstract : Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common neurodegenerative diseases in the world. It has been possible to identify common denominators for AD and PD, including aggregation of the amyloid proteins amyloid-beta (Aβ) and alpha-synuclein (α-syn). READ MORE
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3. Dynamics of proteinopathies in Alzheimer’s disease as measured by PET and CSF biomarkers
Abstract : Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the extracellular aggregation of the amyloid-β (Aβ; amyloid) peptide and the intraneuronal accumulation of the protein tau. Independently, and in concert, these protein opathies lead to the loss of synapses and neurons (neurodegeneration). READ MORE
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4. On Aging, Behavior and the Role of PA28αβ in Protein Homeostasis
Abstract : As life expectancy increases, understanding challenges related to the processes of aging are more relevant than ever. Common age-related diseases progress as consequences of accumulative protein damage and protein aggregates. READ MORE
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5. Investigation of the intercellular transmission of α-synuclein, amyloid-β and TDP-43
Abstract : Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal lobar dementia (FTLD) and amyotrophic lateral sclerosis (ALS) are disorders characterized by the progressive deposition of proteinaceous inclusions throughout the brain in a predictable manner. Each disease is described by the involvement of different misfolded and aggregated proteins (AD, amyloid-β and tau; PD, α-synuclein; ALS and FTLD, TDP-43) that spread between anatomically connected brain regions, causing cell death in previously healthy regions. READ MORE