Search for dissertations about: "Neurofilament light protein"

Showing result 1 - 5 of 32 swedish dissertations containing the words Neurofilament light protein.

2. 1. Neurofilament light as a marker for neurodegenerative diseases

   Author : Niklas Norgren; Torgny Stigbrand; Roland Carlsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Neurofilament protein; ELISA; Cerebrospinal fluid; Neurodegenerative diseases; Immunologi; Immunology; Immunologi; immunologi; Immunology;

   Abstract : Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are belived to be important for maintaining the structural integrity and calibre of axons and dendrites thereby influencing the conduction velocity of nerve impulses. READ MORE

4. 2. Diving and the brain

   Author : Anders Rosén; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; brain; central nervous system; decompression sickness; dive research; diving; neuronal damage; saturation diving; tau protein; venous gas embolism; neurofilament light; glial fibrillary acid protein; tau; VGE;

   Abstract : Abstract Introduction There are reports that long-term diving is associated with cognitive impairments. This raises the question if diving itself is harmful to the brain in the absence of decompression sickness or hypoxia. READ MORE

5. 3. Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia

   Author : Gustaf Österlundh; Göteborgs universitet; []
   Keywords : childhood acute lymphoblastic leukemia; methotrexate; neurotoxicity; cerebral blood flow; single photon emission computed tomography; cerebrospinal fluid; neuron-specific enolase; glia fibrillary acidic protein; neurofilament; ascorbyl radical;

   Abstract : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced by systemic high-dose methotrexate (MTX) and intrathecal (IT) MTX due to the risk of late effects. READ MORE

6. 4. Brain parenchymal fraction in healthy individuals and in clinical follow-up of multiple sclerosis

   Author : Mattias Vågberg; Anders Svenningsson; Richard Birgander; Jonathan Gilthorpe; Anne-Marie Landtblom; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain parenchymal fraction; Neurofilament light; Glial fibrillary acidic protein; Brain atrophy; Multiple Sclerosis; Clinical follow-up;

   Abstract : Background Multiple sclerosis (MS) is an autoimmune disease characterised by inflammatory damage to the central nervous system (CNS). Accumulated CNS injury can be quantified as brain atrophy, definable as a reduction in brain parenchymal fraction (BPF). BPF correlate with disability in MS and is used routinely as an endpoint in clinical trials. READ MORE

7. 5. On HIV-1 infection in the central nervous system

   Author : Åsa Mellgren; Göteborgs universitet; []
   Keywords : HIV-1; antiretroviral therapy; cerebrospinal fluid; neurofilament protein; AIDS dementia complex; neuropsychological test;

   Abstract : HIV-1 (hereafter referred to as HIV) is a neurotropic virus that invades the central nervous system (CNS). The CNS is then susceptible to an acute infection and later to CNS opportunistic diseases and AIDS dementia complex (ADC). HIV does not infect the neurons, and neuropathogenesis is largely mediated by the immune system. READ MORE