Search for dissertations about: "Neurofilament light"
Showing result 1 - 5 of 50 swedish dissertations containing the words Neurofilament light.
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1. Neurofilament light as a marker for neurodegenerative diseases
Abstract : Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are belived to be important for maintaining the structural integrity and calibre of axons and dendrites thereby influencing the conduction velocity of nerve impulses. READ MORE
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2. Treatment with the monoclonal antibody rituximab in Multiple Sclerosis : a study based on an academic clinical trial
Abstract : Background: Multiple sclerosis (MS) is a chronic, inflammatory disease, affecting the central nervous system. A growing number of disease modifying treatment alternatives entails a need for an individualised risk-benefit- convenience analysis in the counselling of patients and methods to monitor the treatment effect, including markers for subclinical inflammation. READ MORE
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3. Mapping the Huntington's disease process using cerebrospinal fluid analysis
Abstract : Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder, caused by a CAG-repeat expansion in the HTT-gene. Today there are no disease-modifying therapies (DMTs), but several promising clinical trials are underway, including therapies that reduce mutant huntingtin expression. READ MORE
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4. Markers and mechanisms of abnormal neurovascular development in the preterm infant
Abstract : Background: The extremely preterm infant is at risk of lifelong neurodevelopmental impairments due to brain injuries or abnormal neurovascular development. Mechanisms are largely unknown and biomarkers for adverse outcomes are sparse. READ MORE
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5. Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia
Abstract : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced by systemic high-dose methotrexate (MTX) and intrathecal (IT) MTX due to the risk of late effects. READ MORE