Search for dissertations about: "Neurofilament light"

Showing result 1 - 5 of 26 swedish dissertations containing the words Neurofilament light.

  1. 1. Neurofilament light as a marker for neurodegenerative diseases

    University dissertation from Umeå : Klinisk mikrobiologi

    Author : Niklas Norgren; Umeå universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Neurofilament protein; ELISA; Cerebrospinal fluid; Neurodegenerative diseases; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; immunologi; Immunology;

    Abstract : Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are belived to be important for maintaining the structural integrity and calibre of axons and dendrites thereby influencing the conduction velocity of nerve impulses. READ MORE

  2. 2. Treatment with the monoclonal antibody rituximab in Multiple Sclerosis a study based on an academic clinical trial

    University dissertation from Umeå : Umeå universitet

    Author : Pierre de Flon; Umeå universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; Rituximab; Cytokines; Immunological profile; Neurofilament light; Treatment satisfaction; neurologi; Neurology;

    Abstract : Background: Multiple sclerosis (MS) is a chronic, inflammatory disease, affecting the central nervous system. A growing number of disease modifying treatment alternatives entails a need for an individualised risk-benefit- convenience analysis in the counselling of patients and methods to monitor the treatment effect, including markers for subclinical inflammation. READ MORE

  3. 3. Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia

    University dissertation from Umeå : Umeå universitet

    Author : Gustaf Österlundh; Göteborgs universitet.; Gothenburg University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; childhood acute lymphoblastic leukemia; methotrexate; neurotoxicity; cerebral blood flow; single photon emission computed tomography; cerebrospinal fluid; neuron-specific enolase; glia fibrillary acidic protein; neurofilament; ascorbyl radical;

    Abstract : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced by systemic high-dose methotrexate (MTX) and intrathecal (IT) MTX due to the risk of late effects. READ MORE

  4. 4. Brain parenchymal fraction in healthy individuals and in clinical follow-up of multiple sclerosis

    University dissertation from Umeå : Umeå universitet

    Author : Mattias Vågberg; Umeå universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain parenchymal fraction; Neurofilament light; Glial fibrillary acidic protein; Brain atrophy; Multiple Sclerosis; Clinical follow-up;

    Abstract : Background Multiple sclerosis (MS) is an autoimmune disease characterised by inflammatory damage to the central nervous system (CNS). Accumulated CNS injury can be quantified as brain atrophy, definable as a reduction in brain parenchymal fraction (BPF). BPF correlate with disability in MS and is used routinely as an endpoint in clinical trials. READ MORE

  5. 5. Neurological consequences of cardiac arrest

    University dissertation from Umeå : Umeå universitet

    Author : Hans Rosén; Göteborgs universitet.; Gothenburg University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiac arrest; prognosis; S-100; NSE; Neurofilament light protein; FIM; BNIS;

    Abstract : An out-of-hospital cardiac arrest is a life-threatening event with very high early mortality. More than 50% of the patients who reach the emergency ward die, showing clinical signs of brain damage during the first weeks after admission. Survivors may suffer from post-ischemic encephalopathy, which influences their future lives. READ MORE