Search for dissertations about: "Neurofilament"

Showing result 1 - 5 of 70 swedish dissertations containing the word Neurofilament.

  2. 1. Neurofilament light as a marker for neurodegenerative diseases

    Author : Niklas Norgren; Torgny Stigbrand; Roland Carlsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Neurofilament protein; ELISA; Cerebrospinal fluid; Neurodegenerative diseases; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Abstract : Neurofilaments are the main cytoskeletal constituents in neuronal cells. They are belived to be important for maintaining the structural integrity and calibre of axons and dendrites thereby influencing the conduction velocity of nerve impulses. READ MORE

  4. 2. Impulse noise and brain injury. An experimental study in rats

    Author : Annette Säljö Moberg; Göteborgs universitet; []
    Keywords : apoptosis; astrocytes; brain injury; blast; c-Fos; c-Jun; c-Myc; impulse noise; ; neurons; neurofilament; NSE; rat and S-100;

    Abstract : Abstract. Pressure waves, experienced as impulse noise, affect many body organs, although most attention has been paid to the inner ear. Impulse noise is produced by e.g. READ MORE

  5. 3. Nerve tissue injury markers, inflammatory mechanisms and immunologic factors in lumbar disc herniation. Clinical and experimental studies

    Author : Helena Brisby; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Disc herniation; sciatica; intervertebral disc; nucleus pulposus; nerve root; neurofilament; S-100; cytokines; nitric oxide; glycosphingolipids.;

    Abstract : The general concept for sciatic pain has for many decades been mechanical nerve root compression caused by a herniated disc. Recently evidence has indicated a more complex process, with a combination of mechanical and inflammatory/immunologic factors involved. READ MORE

  6. 4. Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia

    Author : Gustaf Österlundh; Göteborgs universitet; []
    Keywords : childhood acute lymphoblastic leukemia; methotrexate; neurotoxicity; cerebral blood flow; single photon emission computed tomography; cerebrospinal fluid; neuron-specific enolase; glia fibrillary acidic protein; neurofilament; ascorbyl radical;

    Abstract : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced by systemic high-dose methotrexate (MTX) and intrathecal (IT) MTX due to the risk of late effects. READ MORE

  7. 5. Tau and neurofilament proteins in Alzheimer’s disease and related cell models

    Author : Cecilia Björkdahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AD; tau; neurofilament proteins; kinases; zinc; Hsp27; alphaB-crystallin;

    Abstract : Background and aims: Among those afflicted with dementia more than half suffer from Alzheimer’s disease (AD). Pathological hallmarks of the disease include aggregates of Abeta, so called amyloid plaques, and neurofibrillary tangles (NFTs) made up of hyperphosphorylated cytoskeletal proteins. READ MORE