Search for dissertations about: "Neuromuscular junctions"

Showing result 1 - 5 of 15 swedish dissertations containing the words Neuromuscular junctions.

  1. 1. Modulation of Neuronal Functions the Role of SLC10A4

    University dissertation from Uppsala : Uppsala universitet

    Author : Kalicharan Patra; Uppsala universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; acetylcholine; central nervous system; neuromuscular junctions; electrophysiology; monoamine; synaptic transmission; neuromodulation; Neuroscience; Neurovetenskap;

    Abstract : Mental health of a person depends on the correct functioning of the brain. The brain and the spinal cord contain many types of cells, of which one important type are called the neurons. Neurons are special in the way they connect to each other to form large networks. READ MORE

  2. 2. Function and targets of the Urm1/Uba4 conjugation machinery in Drosophila melanogaster

    University dissertation from Umeå : Umeå University

    Author : Behzad Khoshnood; Umeå universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Urm1; Uba4; MOCS3; Tax; HTLV; Posttranslational modification; ubiquitin-like modifiers; UBL; PTM; JNK; neuromuscular junctions; signaling; molekylärbiologi; Molecular Biology;

    Abstract : Posttranslational modification (PTM) of proteins is essential to maintain homeostasis and viability in all eukaryotic cells. Hence, besides the sequence and 3D folding of a polypeptide, modification by multiple types of PTMs, ranging from small molecular groups to entire protein modules, adds another layer of complexity to protein function and regulation. READ MORE

  3. 3. A Muscle Perspective on the Pathophysiology of Amyotrophic Lateral Sclerosis Differences between extraocular and limb muscles

    University dissertation from Umeå : Umeå universitet

    Author : Vahid M. Harandi; Umeå universitet.; Umeå universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuromuscular junctions; Extraocular muscles; Skeletal muscle; Neurotrophic factor; Wnt; Motor neuron disease; Amyotrophic lateral sclerosis; SOD1G93A mice; molekylärbiologi; Molecular Biology;

    Abstract : Background: Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disorder. ALS has been traditionally believed to be primarily a motor neuron disease. READ MORE

  4. 4. Morphologican and functional studies on the Drosophila neuromuscular system during postembryonic stages

    University dissertation from Stockholm : Zoologiska institutionen

    Author : Ana Beramendi; Stockholms universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drosophila; neuromuscular system; Rel-proteins; fly brain; rhythmic morphology; aging; ; MEDICINE Physiology and pharmacology Physiology Neurobiology; MEDICIN Fysiologi och farmakologi Fysiologi Neurobiologi;

    Abstract : The nervous system of the fruit fly Drosophila melanogaster has emerged as an excellent model for fundamental neuroscience as well as for biomedical research of human neurological diseases. In this thesis, two aspects of the neuromuscular system have been investigated: the role of the IkB-protein Cactus in the larval neuromuscular junction and the morphology of motor terminals throughout adult life. READ MORE

  5. 5. Extraocular Muscles in Amyotrophic Lateral Sclerosis

    University dissertation from Umeå : Umeå universitet

    Author : Anton Tjust; Umeå universitet.; Umeå universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; EOM; Satellite cells; innervation; neuromuscular disease; neurodegenerative disease; anatomi; Human Anatomy;

    Abstract : Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease of motor neurons characterized by muscle paralysis and death within 3-5 years of onset. However, due to unknown mechanisms, the extraocular muscles (EOMs) remain remarkably unaffected. READ MORE