Search for dissertations about: "Neurosurgery trauma"

Showing result 1 - 5 of 8 swedish dissertations containing the words Neurosurgery trauma.

  2. 1. Sensory neuronal protection & improving regeneration after peripheral nerve injury

    Author : Andrew McKay Hart; Mikael Wiberg; Angus McGrouther; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; cell death; TUNEL; optical disection; dorsal root ganglion; peripheral nerve; nerve conduit; Schwann cell; glial growth factor; leukaemia inhibitory factor; acetyl-L-carnitine; N-acetyl-cysteine; Neurovetenskap; Neurology; Neurologi; neurokirurgi; Neurosurgery;

    Abstract : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. READ MORE

  4. 2. Pressure autoregulation of cerebral blood flow in traumatic brain injury and aneurysmal subarachnoid hemorrhage

    Author : Ulf Johnson; Per Enblad; Lars-Owe Koskinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral blood flow; autoregulation; traumatic brain injury; subarachnoid hemorrhage; Neurosurgery; Neurokirurgi;

    Abstract : The ability of the brain to keep a stable and adequate cerebral blood flow (CBF) independently of fluctuations in systemic blood pressure is referred to as cerebral pressure autoregulation (CPA). When the brain is injured by trauma or hemorrhage, this ability may be impaired, leaving the brain vulnerable to events of high or low blood pressure. READ MORE

  5. 3. Mechanisms of traumatic brain injury in the rat : Morphological consequences and neurotrophic responses

    Author : Anders Lewén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Cortical contusion injury; TBI; neurons; axons; dendrites; APP; MAP2; BMPR-II; ActR-I; trkB; c-fos; BDNF; PACAP; TUNEL; TGFs; serine threonine; bone morphogenetic protein; neuropeptides; reactive oxygen species; ROS; apoptosis; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

    Abstract : Traumatic brain injury is a major cause of death and disability in the Western world. especially in young people. Understanding the pathophysiology of traumatic brain injury is the basis for further development of better therapeutic strategies for such patients. READ MORE

  6. 4. Biosynthetic conduits and cell transplantation for neural repair

    Author : Jonas Pettersson; Lev Novikov; Liudmila Novikova; Mikael Wiberg; Lars Dahlin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spinal cord injury; Peripheral nerve injury; Nerve graft; Biosynthetic conduit; Nerve tissue engineering; Neural prosthesis; Neuroscience; Neurovetenskap; neurologi; Neurology; neurokirurgi; Neurosurgery;

    Abstract : Spinal cord injury results in complete failure of the central neurons to regenerate and is associated with cyst formation and enlargement of the trauma zone. In contrast to the spinal cord, axons in the injured peripheral nerve have the capacity to undergo some spontaneous regeneration. READ MORE

  7. 5. On optic nerve injury : experimental studies on axonal regeneration in the adult mammalian CNS

    Author : Marcus Ohlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Astroglia; axon; degeneration; glial scar; immunohistochemistry; macrophage; methylprednisolone; microglia; neurosurgery; optic nerve; rat; regeneration and visual evoked potentials;

    Abstract : Optic nerve injury may occur after a trauma to the head and in many cases it causes partial or total blindness. Today, these patients cannot be offered any specific treatment to restore visual function. READ MORE