Search for dissertations about: "Next-Generation Sequence"
Showing result 1 - 5 of 52 swedish dissertations containing the words Next-Generation Sequence.
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1. Next generation molecular diagnostics using ultrasensitive sequencing
Abstract : Massively parallel sequencing enables the exploration of the genetic heterogeneity within microbial, viral and tumor cell populations. Detecting circulating tumor DNA in blood and other body fluids has the potential to revolutionize molecular diagnostics. READ MORE
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2. Next-generation Molecular Systematics and Evolution: insights into Medicago
Abstract : Evolutionary relationships among species have in recent years been inferred using DNA sequences from specific genes and represented by tree diagrams (phylogenies). However, the signal contained in different genes can produce conflicting sets of relationships – i.e., gene tree incongruence. READ MORE
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3. Birds as a Model for Comparative Genomic Studies
Abstract : Comparative genomics provides a tool to investigate large biological datasets, i.e. genomic datasets. In my thesis I focused on inferring patterns of selection in coding and non-coding regions of avian genomes. READ MORE
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4. Hidden patterns that matter : statistical methods for analysis of DNA and RNA data
Abstract : Understanding how the genetic variations can affect characteristics and function of organisms can help researchers and medical doctors to detect genetic alterations that cause disease and reveal genes that causes antibiotic resistance. The opportunities and progress associated with such data come however with challenges related to statistical analysis. READ MORE
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5. Exploring genetic diversity in natural and domestic populations through next generation sequencing
Abstract : Studying genetic diversity in natural and domestic populations is of major importance in evolutionary biology. The recent advent of next generation sequencing (NGS) technologies has dramatically changed the scope of these studies, enabling researchers to study genetic diversity in a whole-genome context. READ MORE