Search for dissertations about: "Next-generation sequencing"

Showing result 1 - 5 of 113 swedish dissertations containing the words Next-generation sequencing.

  1. 1. Exploring next-generation sequencing in chronic lymphocytic leukemia

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Viktor Ljungström; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CLL; next-generation sequencing; clonal evolution; stereotypy; RPS15; NFKBIE; Medical Genetics; Medicinsk genetik;

    Abstract : Next-generation sequencing (NGS) techniques have led to major breakthroughs in the characterization of the chronic lymphocytic leukemia (CLL) genome with discovery of recurrent mutations of potential prognostic and/or predictive relevance. However, before NGS can be introduced into clinical practice, the precision of the techniques needs to be studied in better detail. READ MORE

  2. 2. Tagging systems for sequencing large cohorts

    University dissertation from Stockholm

    Author : Mårten Neiman; KTH.; KTH.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; next generation sequencing; genotyping; massive parallel sequencing; 454; Pyrosequencing; amplicon sequencing; enrichment; DNA barcodes; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik;

    Abstract : Advances in sequencing technologies constantly improves the throughput andaccuracy of sequencing instruments. Together with this development comes newdemands and opportunities to fully take advantage of the massive amounts of dataproduced within a sequence run. READ MORE

  3. 3. Methods to Prepare DNA for Efficient Massive Sequencing

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Sverker Lundin; KTH.; [2012]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA; Massive sequencing; Next Generation Sequencing; Library Preparation; Barcoding; Multiplexing;

    Abstract : Massive sequencing has transformed the field of genome biology due to the continuous introduction and evolution of new methods. In recent years, the technologies available to read through genomes have undergone an unprecedented rate of development in terms of cost-reduction. READ MORE

  4. 4. Data Analysis and Next Generation Sequencing : Applications in Microbiology

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Nicolas Innocenti; KTH.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; RNA-seq; tagRNA-seq; primary and processed RNA; Enterococcus faecalis; Complex transcription; Metagenomics; 5 tagRACE; minimal absent words; compressed sensing; metagenomics; bacterial community reconstruction; Biological Physics; Biologisk fysik;

    Abstract : Next Generation Sequencing (NGS) is a new technology that has revolutionized the way we study living organisms. Where previously only a few genes could be studied at a time through targeted direct probing, NGS offers the possibility to perform measurements for a whole genome at once. READ MORE

  5. 5. Exploring genetic diversity in natural and domestic populations through next generation sequencing

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Nima Rafati; Uppsala universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ecological adaptation; seasonal reproduction; Atlantic herring; domestication; speciation; rabbit; skeletal atavism; Shetland ponies; NGS; SMRT sequencing; genome; transcriptome; assembly; structural variation; genetic diversity; HCE; TSHR; SHOX; CRLF2;

    Abstract : Studying genetic diversity in natural and domestic populations is of major importance in evolutionary biology. The recent advent of next generation sequencing (NGS) technologies has dramatically changed the scope of these studies, enabling researchers to study genetic diversity in a whole-genome context. READ MORE