Search for dissertations about: "Nicole Zache"
Found 1 swedish dissertation containing the words Nicole Zache.
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1. Studies of mutant p53-targeting small molecules
Abstract : Multiple cellular stresses, such as DNA damage, oncogene activation, hypoxia, and telomere erosion induce p53 protein levels leading to an array of biological responses, including cell cycle arrest and apoptosis. p53 exerts its function mainly through transcriptional regulation of specific target genes, but is also able to induce transcriptional-independent apoptosis. READ MORE
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