Search for dissertations about: "Niklas Mejhert"

Found 2 swedish dissertations containing the words Niklas Mejhert.

  2. 1. Characterization of adipose factors regulated by body weight

    Author : Niklas Mejhert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : White adipose tissue (WAT) constitutes our most expandable tissue and largest endocrine organ secreting hundreds of polypeptides collectively termed adipokines. Changes in WAT mass induce alterations in adipocyte secretion and function, which are linked to disturbed whole-body metabolism. READ MORE

  4. 2. Pharmacological and genetic manipulation of adipose cell differentiation and metabolism

    Author : Milica Vranic; Maria J. Pereira; Jan Eriksson; Niklas Mejhert; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; adipocyte; type 2 diabetes; CRISP Cas9; FKBP51; CDKN2C; second-generation antipsychotics; glucocorticoids; dopamine; dopamine receptor;

    Abstract : Adipose tissue dysfunction has a pivotal role in the development of obesity and related metabolic complications, such as insulin resistance, cardiovascular disease, and diabetes. The overall aim was to study the consequences of adipose exposure to pharmacological agents, as well as dysregulations in the expression of genes, potentially involved in adipose tissue dysfunction and related metabolic impairments. READ MORE