Search for dissertations about: "Nina Rökaeus"

Found 1 swedish dissertation containing the words Nina Rökaeus.

2. 1. Pharmacological targeting of mutant p53 family members

   Author : Nina Rökaeus; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The tumor suppressor p53 serves as a guardian of the genome and functions mainly as a transcription factor. In response to various stress signals p53 binds to specific DNA sequence motifs and regulates transcription of a large group of target genes involved in cellular processes such as cell cycle arrest, senescence and apoptosis. READ MORE