Search for dissertations about: "Nitric oxide in experimental sepsis"

Showing result 1 - 5 of 7 swedish dissertations containing the words Nitric oxide in experimental sepsis.

2. 1. Nitric oxide in experimental sepsis

   Author : Peter Dahm; Anestesiologi och intensivvård; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; Nitric oxide; Sepsis; NO inhalation; Endotoxin; Acute lung injury; ARDS; Nitric oxide synthase; L-NMMA; L-NAME; Anestesiologi; Anaesthesiology; Pigs; intensivvård;

   Abstract : Nitric oxide (NO) is important in the control of blood pressure and organ perfusion. In septic shock, NO produced by inducible NO-synthase (NOS) has been claimed to mediate pathological vasodilation and cell injury, while NO produced by constitutive NOS may be protective in counteracting hypoperfusion and organ injury. READ MORE

4. 2. Nitric oxide and extravasation in endotoxaemia : an experimental study

   Author : Kerstin Metcalf; Mikael Bodelsson; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Background: Despite advances in intensive care the mortality of patients in septic shock is still high. In early stages the condition is characterised by circulatory failure that is a consequence of myocardial depression, vasodilatation with decreased sensitivity to catecholamine stimulation and increased loss of protein and fluid from the circulation. READ MORE

5. 3. Endogenous Nitric Oxide Production and Pulmonary Blood Flow : during different experimental lung conditions

   Author : Manja Nilsson; Filip Fredén; Kristina Hambraeus-Jonzon; Göran Hedenstierna; Eddie Weitzberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nitric oxide; pulmonary blood flow; endotoxin; nitric oxide inhalation; endothelin; hypercapnia; acidosis; lavage-induced lung injury; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Abstract : Nitric oxide (NO) is an important regulator of pulmonary blood flow and attenuates hypoxic pulmonary vasoconstriction (HPV). Nitric oxide is synthesized enzymatically in a number of tissues, including the lungs, and can also be generated from reduction of nitrite during hypoxia and acidosis. READ MORE

6. 4. Nasal airway nitric oxide : methodological aspects and influence of inflammation

   Author : Jörgen Palm; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Asthma; breath test; exhaled air; rhinitis; sinuses; sinusitis; diurnal variation; gender; nasal; oral; nitric oxide; volume flow rate; AIDS; HIV; endotoxin; gut; human; shock; allergy.;

   Abstract : Nitric oxide (NO) is an endogenously formed free radical gas involved in numerous biological processes. In 1991 NO was discovered to be present in exhaled air of humans. Soon after, it was reported that the largest amounts of NO were found in the upper airways, and that the levels of NO were increased in the lower airways of patients with asthma. READ MORE

7. 5. Biomarkers in endotoxemia with a special interest in citrullinated histone H3

   Author : Sofie Paues Göranson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Sepsis with multi-organ failure has an unacceptably high mortality rate of 25- 30% despite the use of antibiotics and modern intensive care. Attenuating the multi-organ failure and finding new biomarkers for early detection of septic shock would be of high clinical relevance in order to improve outcome. READ MORE