Search for dissertations about: "Nkx3.2"

Found 2 swedish dissertations containing the word Nkx3.2.

  2. 1. The role of Nkx3.2 and Gdf5 during zebrafish skeletal development

    Author : Laura Waldmann; Tatjana Haitina; Abigail Tucker; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nkx3.2; Gdf5; zebrafish; jaw joint; joints; axial skeleton; appendicular skeleton; fin; enhancer conservation; CRISPR Cas9; OPT;

    Abstract : The vertebrate skeleton is composed of bony and cartilaginous structures that are developed under the control of numerous genetic networks. The transcription factor Nkx3. READ MORE

  4. 2. Musculoskeletal Development in Jawed Vertebrates : Gene function, cis-regulation, and 3D phenotypes in zebrafish

    Author : Jake Leyhr; Tatjana Haitina; Sophie Sanchez; Per Ahlberg; Chrissy Hammond; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nkx3.2; Gdf5; Mkx; zebrafish; jaw joint; skeleton; fin development; cartilage; tendon; ligament; enhancer; CRISPR Cas9; mutant; microCT; synchrotron; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Abstract : Vertebrate skeletons are an intricate framework of bony and cartilaginous structures that form through carefully orchestrated developmental processes, guided by interacting genetic pathways that regulate cellular differentiation, migration, and tissue morphogenesis. The specific timing and localisation of gene expression shapes the diverse array of skeletal elements, from the flexible cartilages of the embryonic stage to the hardened bones that provide structural support in adulthood, and the joints and connective tissues that articulate the musculoskeletal system. READ MORE