Search for dissertations about: "Non clinical research"
Showing result 1 - 5 of 864 swedish dissertations containing the words Non clinical research.
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1. Mapping the Huntington's disease process using cerebrospinal fluid analysis
Abstract : Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder, caused by a CAG-repeat expansion in the HTT-gene. Today there are no disease-modifying therapies (DMTs), but several promising clinical trials are underway, including therapies that reduce mutant huntingtin expression. READ MORE
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2. Insulin Resistance : Causes, biomarkers and consequences
Abstract : The worldwide increasing number of persons affected by largely preventable diseases like diabetes demands better prevention and treatment. Insulin is required for effective utilisation of circulating nutrients. READ MORE
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3. Norovirus and rotavirus susceptibility : studies from a Nicaraguan birth cohort
Abstract : Norovirus and rotavirus are major causes of pediatric acute gastroenteritis (AGE). It is estimated that norovirus is responsible for ~20% of all diarrheal diseases in children worldwide and causes approximately 200,000 deaths each year, mostly in young children and the elderly. READ MORE
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4. Nuclease Activity as a Biomarker in Cancer Detection
Abstract : Nucleases are a group of enzymes that cleave the phosphodiester bonds in nucleic acids. As such, nucleases act as biological scissors that exhibit a plethora of fundamental roles, in prokaryotes and eukaryotes, dependent or non-dependent on their catalytic capability. READ MORE
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5. Depression in teenagers and young adults : foundational studies of the new treatment paradigm TARA: Training for Awareness, Resilience, and Action
Abstract : Introduction: Depression in adolescents and young adults is an increasing global health concern and available treatments are not convincingly effective. It is therefore important to develop and test novel treatments to improve treatment outcomes. READ MORE