Search for dissertations about: "Non-steroidal"

Showing result 11 - 15 of 58 swedish dissertations containing the word Non-steroidal.

  2. 11. Estrogen receptor and multixenobiotic resistance genes in freshwater fish and snails: identification and expression analysis after pharmaceutical exposure

    Author : Cecilia Hultin; Miljövetenskap; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; EE2; NSAID; estrogen receptor; oestrogen receptor; multixenobiotic resistance; fish; gastropods;

    Abstract : Pharmaceuticals are today released into aquatic environments where they can interfere with organisms' biological processes.The general research objective was to analyze how aquatic freshwater organisms are affected by exposure to pharmaceuticals that are categorized by the EU as potential risk factors to the environment (i.e. READ MORE

  4. 12. Granulocyte activation by danger signals and blocking of receptor responses

    Author : Anna-Lena Stenfeldt; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; granulocytes; neutrophils; eosinophils; danger signals; danger theory; formyl peptide receptors; antagonists; inhibitors;

    Abstract : Granulocytes are the most abundant cells in the peripherial blood. They serve to eliminate invading microbes and parasites and release anti-microbial agents. In the event of injury, granulocytes are recruited to damaged tissues. READ MORE

  5. 13. Involvement of Eicosanoid Signaling in Intestinal Epithelial Cell Survival

    Author : John Öhd; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; Tcf Lef; Bcl-2 family; b-catenin; 5-LO; apoptosis; cell survival; colorectal cancer; COX-2; LTD4; CysLT1 R; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Abstract : Eicosanoids are known to be involved in many different aspects of eukaryotic physiology and pathology. Notably, over the past 10 years much attention has been given to cyclooxygenase-2 (COX-2) due to its involvement in colorectal cancer. Less is known about the other major branch of arachidonic acid metabolism, namely the lipoxygenases (LO). READ MORE

  6. 14. Angiotensin converting enzyme inhibition and aspirin in congestive heart failure

    Author : Tord Juhlin; Kardiologiska klinikens forskargrupp; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical trial; ARBs; renal function; congestive heart failure; ischaemic heart disease; NSAIDs; ACE-inhibitors; aspirin; dose dependency; Cardiovascular system; Kardiovaskulära systemet;

    Abstract : Angiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. READ MORE

  7. 15. Associations Between Rheumatoid Arthritis and Malignant Lymphomas

    Author : Eva Baecklund; Christer Sundström; Anders Ekbom; Roger Hällgren; Tore Kvien; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; rheumatoid arthritis; malignant lymphoma; diffuse large B-cell lymphoma; disease activity; disease modifying anti-rheumatic drug; Epstein-Barr virus; germinal centre-like non-germinal centre-like subtype; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : Patients with rheumatoid arthritis (RA) are at increased risk of developing malignant lymphoma, although details about this association remain unclear. The aims of this thesis were to investigate risk factors for lymphoma in patients with RA and to characterize these lymphomas regarding subtype, presence of Epstein-Barr virus (EBV), clinical manifestations and prognosis. READ MORE