Search for dissertations about: "Non-steroidal"

Showing result 16 - 20 of 58 swedish dissertations containing the word Non-steroidal.

  2. 16. Inhibition of mPGES-1 as therapeutic strategy in inflammation and cancer

    Author : Filip Bergqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prostaglandin E2 (PGE2) is an inflammatory and oncogenic lipid mediator. It is mainly formed via metabolism of arachidonic acid by cyclooxygenases (COX-1 and COX-2) and the terminal enzyme microsomal prostaglandin E synthase-1 (mPGES-1). READ MORE

  4. 17. Quantification of left-to-right shunt through Patent Ductus Arteriosus by colour Doppler

    Author : Solweig Harling; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The aim of this thesis was to develop a non-invasive method to quantify the size of a shunt through a patent ductus arteriosus (PDA) by ultrasound and to test its usability in clinical settings. There is no consensus regarding the optimal management strategy for a PDA in premature infants. READ MORE

  5. 18. Computational studies of photodynamic drugs, phototoxic reactions and drug design

    Author : Klefah Abrahem Klefah Musa; Leif Eriksson; Nino Russo; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NSAIDs; fluoroquinolone; photodegradation; phototoxicity; drug design; DFT; TD-DFT; Biophysical chemistry; Biofysikalisk kemi; Chemistry; Kemi;

    Abstract : The most important criterion when designing new drugs or improving old ones in order to prevent side effects or at least diminish them is drug safety. Treatment of all diseases generally needs use of either topical application or systemic medications (transported in the blood) during a certain period of time. READ MORE

  6. 19. Investigation of degradation of toxic substances in fungal cultures by mass spectrometric techniques

    Author : Åke Stenholm; Mikael Hedeland; Pablo Campo Moreno; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; UHPLC-Q-TOF MS; filamentous fungi; immobilization; polyurethane foam; removal; biodegradation products; Analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Abstract : Micropollutants in water are biological or chemical contaminants that are present in ground and surface waters in trace quantities. They are a result of human activity and include pharmaceutically active compounds (PhACs) and endocrine disrupting compounds (EDCs). READ MORE

  7. 20. Analytical method development for ultra-trace determination of human pharmaceuticals in aqueous samples. Assessing the performance of a sewage treatment plant

    Author : Saioa Zorita; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molecularly imprinted solid-phase extraction; Sample preparation; solid-phase extraction; membrane extraction; human pharmaceuticals; sewage treatment plant; steroid hormones;

    Abstract : Research focus in environmental pollution has recently been extended from more classical environmental pollutants such as PCBs or pesticides to pharmaceuticals and steroid hormones, which are designed to be biologically active and enter the environment primarily through regular domestic use. Consequently, it is important to monitor these substances concentrations in the effluents of sewage treatment plants (STPs) and in the environment in order to evaluate their associated risks. READ MORE