Search for dissertations about: "Non-steroidal"

Showing result 6 - 10 of 58 swedish dissertations containing the word Non-steroidal.

  2. 6. Cyclooxygenase-2 inhibitors and knee prosthesis surgery

    Author : Andreas Meunier; Lars Good; Per Aspenberg; Tore Dalén; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-steroidal anti-inflammatory agents; administration dosage; Arthroplasty; knee replacement; Surgical blood loss; Surgery; Cyclooxygenase inhibitors; Cyclooxygenase inhibitors; Fracture healing; Isoxazoles; Postoperative pain; Pyrazoles; Sulfonamides; Surgery; Kirurgi;

    Abstract : Adverse effects of cyclooxygenase (COX) inhibitors on bone healing have previously been demonstrated in diaphyseal fracture models in animals. In spite of that, they are widely used as postoperative analgesics in orthopaedic surgery. After joint replacement, a bone repair process starts at the interface between bone and cement. READ MORE

  4. 7. Evaluation of polysucrose 15000 as a marker of intestinal permeability

    Author : Hans Öman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Polysucrose Permeability Intestinal Absorption Cell Memhrane Permeahility Molecular WeightMacromolecular systems Biological Markers Biological Transport Crohn Disease Arthritis; RheumatoidAnti-lnflammatory Agents; Non-Steroidal Chromium Radioisotop;

    Abstract : Polysucrose (PS) is a synthetic copolymer of sucrose and epichlorohydrin, which can be produced in a variety of molecular sizes. The aim of the study was to evaluate the functionality of PS 15000, mean mol wt 14700, as a marker for intestinal permeability to macro molecules. READ MORE

  5. 8. Improving medical abortion : using mifepristone in combination with a prostaglandin analogue

    Author : Christian Fiala; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Medical abortion; mifepristone; misoprostol; slow release; home use; hCG; ultrasound; verification of expulsion; non-steroidal anti-inflammatory drug; pain relief; second trimester; uterine contractility; acceptability;

    Abstract : Background: Induced abortion is still a major health problem in the world and the most frequently performed intervention in Obstetrics and Gynaecology with an estimated total of 46 millions worldwide each year. Medical abortion with mifepristone and prostaglandin was first introduced in 1988, and is now approved in 29 countries. READ MORE

  6. 9. Aspects on the etiology of esophageal and gastric cancer

    Author : Mats Lindblad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Esophageal; gastric; gastric cardia; cancer; cancer register; misclassification; epidemiology; incidence; etiology; estrogen; aspirin; non-steroidal anti-inflammatory drugs; body mass; tobacco; alcohol; adenocarcinoma; squamous-cell carcinoma;

    Abstract : In a global perspective esophageal and gastric cancer present major health concerns, whereas these tumors are comparatively uncommon in most western countries. Striking and hitherto unexplained rising incidence trends of esophageal adenocarcinoma, and moderately increasing rates of gastric cardia adenocarcinoma have recently been reported from several western countries, however. READ MORE

  7. 10. Protein Engineering of Candida antarctica Lipase A : Enhancing Enzyme Properties by Evolutionary and Semi-Rational Methods

    Author : Anders G. Sandström; Jan-Erling Bäckvall; Uwe T. Bornscheuer; Stockholms universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lipase; protein engineering; directed evolution; kinetic resolution; structural biology; Enzyme engineering; Enzymteknik; organisk kemi; Organic Chemistry;

    Abstract : Enzymes are gaining increasing importance as catalysts for selective transformations in organic synthetic chemistry. The engineering and design of enzymes is a developing, growing research field that is employed in biocatalysis. READ MORE