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Showing result 1 - 5 of 68 swedish dissertations matching the above criteria.
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1. Improved dose response modeling for normal tissue damage and therapy optimization
Abstract : The present thesis is focused on the development and application of dose response models for radiation therapy. Radiobiological models of tissue response to radiation are an integral part of the radiotherapeutic process and a powerful tool to optimize tumor control and minimize damage to healthy tissues for use in clinical trials. READ MORE
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2. Predicting Normal Tissue Complications after External Beam Radiation Therapy
Abstract : Although modern external beam radiation (EBRT) therapy has the ability to conform the dose tightly around the volume to be treated, unwanted irradiation to surrounding normal tissue is still a problem. The probability of a side effect arising in normal tissue after EBRT is commonly modelled by an s-shaped dose-volume response curve where dose or volume are plotted against response (i. READ MORE
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3. Predicting Normal Tissue Complications after External Beam Radiation Therapy
Abstract : .... READ MORE
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4. On the biological response to different biomaterials under normal and irradiated conditions
Abstract : There are several challenges when introducing an implant into a host. Concerning soft tissues, major complications are fibrosis and capsule contracture, whereas for bone, failure of osseointegration may occur. READ MORE
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5. Interplay between hormones, nutrients and adipose depots in the regulation of insulin sensitivity : an experimental study in rat and human adipocytes
Abstract : Obesity and specifically central obesity is related to insulin resistance, type 2 diabetes and other components of the so-called metabolic syndrome. The aim of this study was to elucidate the interplay between hormones, nutrients and adipose depots in normal and insulin-resistant fat cell metabolism. READ MORE