Search for dissertations about: "Novel bacteria"

Showing result 1 - 5 of 411 swedish dissertations containing the words Novel bacteria.

  2. 1. Uncovering novel cell wall chemistries in gram negative bacteria : from development or dedicated peptidoglycan chemometric tools to functional genomics

    Author : Akbar Espaillat; Felipe Cava; Sun Nyunt Wai; Waldemar Vollmer; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bacteria; cell wall; peptidoglycan; peptidoglycan variations; D-amino acids; molekylärbiologi; Molecular Biology;

    Abstract : Bacteria are surrounded by an external cell wall whose main component is a polymeric net-like structure called the peptidoglycan (PG) or murein sacculus. PG plays crucial roles in bacterial physiology (eg morphogenesis, growth fitness and regulation of innate immunity). READ MORE

  4. 2. Towards novel antibacterials : Synthesis and identification of natural product inspired inhibitors of Chlamydia trachomatis and development of chemical probes targeting virulence of Pseudomonas aeruginosa

    Author : Michael Saleeb; Mikael Elofsson; Anna Linusson Jonsson; Andreas Kirschning; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibacterials; antibiotics; small molecules; natural products; benzofuran; dihydrobenzofuran; the type III secretion system; Pseudomonas aeruginosa; Chlamydia trachomatis; phenotypic screening; high-throughput screening; surface plasmon resonance; drug discovery; bacterial toxins; enzyme inhibitors; organisk kemi; Organic Chemistry;

    Abstract : Antibiotic resistance has evolved significantly to become one of the serious threats to public health today. Yet, the pipeline of new antibiotics is drying up and is lagging behind the challenging needs. READ MORE

  5. 3. Towards time-resolved molecular interaction assays in living bacteria

    Author : João Crispim Encarnação; Karl Andersson; Marika Nestor; U. Helena Danielson; Hélène Munier-Lehmann; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intracellular Molecular Interactions; Real-Time Cell Binding Assays; Bacteria; LigandTracer; Kinetics; Biokemi; Biochemistry; Biofarmaci; Biopharmaceutics; Medicinsk vetenskap; Medical Science;

    Abstract : Rare and neglected diseases such as multidrug resistant (MDR) tuberculosis, malaria and trypanosomiasis are re-emerging in Europe. New strategies are needed to accelerate drug discovery to fight these pathogens. READ MORE

  6. 4. Seaweed Invasions and Novel Chemical Defences

    Author : Swantje Enge; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biological invasions; enemy release; increased competitive ability; novel weapon; chemical defence; plant-herbivore interactions; competition; seaweeds; Bonnemaisonia hamifera;

    Abstract : Biological invasions pose a risk to the biodiversity and the functioning of ecosystems in invaded areas. The reasons why some introduced species become dominant and widespread in their new environments is still largely an unsettled question. READ MORE

  7. 5. Novel Endogenous Antimicrobial Peptides

    Author : Emma Nordahl; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; D5; HK; C3a; HMWK; complement; heparin-binding; antibacterial; Antimicrbial peptide; AMP;

    Abstract : Antimicrobial peptides serve as a first line of defence against invading microorganisms and are an essential part of our fast innate immune system. They are ancient molecules found in all classes of life. Antimicrobial peptides rapidly kill a broad spectrum of microbes and are immunomodulatory, i.e. READ MORE