Search for dissertations about: "Nylen"

Showing result 6 - 10 of 45 swedish dissertations containing the word Nylen.

  2. 6. Identification of novel inducers for LL-37 expression : assay development and mechanistic studies

    Author : Frank Nylén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The remaining reservoir of effective antibiotics is running out and more and more pathogens are gaining resistance, even to the last line of antibiotics. Therefore, novel treatment regimens against bacterial infections are urgently needed. READ MORE

  4. 7. Studies on 4b-hydroxycholesterol, a marker of CYP3A activity, and its association with 25-hydroxyvitamin D

    Author : Hanna Nylén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous compounds such as steroids and drugs. READ MORE

  5. 8. Studies on the oxysterols 4alpha- and 4beta-hydroxycholesterol

    Author : Hanna Nylén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cytochrome P450 (CYP) enzymes catalyze the metabolism of both foreign and endogenous substances such as drugs and steroids. Enzymes in subfamily CYP3A sum up to 30% of the total CYP content in the liver and metabolize about 50% of all drugs. READ MORE

  6. 9. Critical potential and oxygen evolution of the chlorate anode

    Author : Linda Nylén; Göran Lindbergh; Yohannes Kiros; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; chlorate; chloride oxidation; oxygen evolution; critical anode potential; chromate; DSA; mass transport; RDE; Chemical engineering; Kemiteknik;

    Abstract : In the chlorate process, natural convection arises thanks to the hydrogen evolving cathode. This increases the mass transport of the different species in the chlorate electrolyte. There is a strong connection between mass transport and the kinetics of the electrode reactions. READ MORE

  7. 10. A role for NK cells in innate immunity against human leishmaniasis

    Author : Susanne Nylén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Leishmania; NK cells; innate immune activation; IFNgamma; vaccine candidates;

    Abstract : Leishmaniasis is a group name for a spectrum of diseases caused by intracellular protozoa belonging to the family Leishmania. The parasites has been widely used as a tool to study the Th1 / Th2 paradigm of resistance and susceptibility in mice. A role of NK cells in leishmaniasis has been implicated, but not fully explored. READ MORE