Search for dissertations about: "Nyström Thomas"

Showing result 1 - 5 of 6 swedish dissertations containing the words Nyström Thomas.

2. 1. Adaptive Design for Circular Business Models in the Automotive Manufacturing Industry

   Author : Thomas Nyström; RISE; []
   Keywords : Circular Business Models; Product Service System; Business and Design Logic; Circular Economy; Design for Circular Business Models;

   Abstract : The vision of a circular economy (CE) promises both profitability and eco-sustainability to industries, and can, from a material and energy resource flow perspective, be operationalized by combining three business and design strategies: closing loops; narrowing and slowing down resource flows by material recycling, improving resource efficiency; and by extending product life by reuse, upgrades and remanufacturing. These three strategies are straightforward ways for industries to radically reduce their use of virgin resources. READ MORE

4. 2. On endothelial function in type 2 diabetic patients with coronary artery disease

   Author : Thomas Nyström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Type 2 diabetes; endothelial dysfunction; insulin resistance; coronary artery disease; nitric oxide; glucagon-like peptide 1; exendin; tetrahydrobiopterin; inflammation; adiponectin; resistin; C-reactive protein; tumor necrosis factor a; interleukin-6;

   Abstract : Patients with type 2 diabetes have a poor outcome suffering a myocardial infarction (MI). Endothelial dysfunction may play a role in this poor prognosis. In type 2 diabetes, endothelial dysfunction is a salient feature coexisting with obesity and insulin resistance and may be linked by the same pathophysiology, i.e. READ MORE

5. 3. The Skorohod problem and weak approximation of stochastic differential equations in time-dependent domains

   Author : Thomas Önskog; Kaj Nyström; Leif Persson; Johan Tysk; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Skorohod problem; weak approximation; time-dependent domain; stochastic differential equations; parabolic partial differential equations; oblique reflection; stopped diffusions; Euler scheme; adaptive methods; sensitivity analysis; financial derivatives; Greeks ; MATHEMATICS; MATEMATIK; Mathematics; matematik;

   Abstract : This thesis consists of a summary and four scientific articles. All four articles consider various aspects of stochastic differential equations and the purpose of the summary is to provide an introduction to this subject and to supply the notions required in order to fully understand the articles. READ MORE

6. 4. On the role of small regulatory molecules in the interplay between σ54- and σ70-dependent transcription

   Author : Linda Holmfeldt; Victoria Shingler; Thomas Nyström; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; σ54; σ70; ppGpp; DksA; transcription regulation; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Abstract : Signal responsive transcriptional control in bacteria is mediated through both specific and global regulatory circuits to attune promoter output to prevailing conditions. Divergent transcription of a regulatory gene and a cognate promoter under its control provides an opportunity for interplay between transcription dependent on RNA polymerases utilizing various σ-factors, each of which programs the holoenzyme to recognize different classes of promoters. READ MORE

7. 5. Insulin-Degrading Enzyme : A link between insulin resistance and Alzheimer's disease

   Author : Helena Kullenberg; Marie Svedberg; Maria Kumlin; Thomas Nyström; Michael Alvarsson; Sophiahemmet Högskola; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Background: Prior research has demonstrated an elevated risk of Alzheimer's disease (AD) among individuals diagnosed with type 2 diabetes mellitus (T2DM). Insulin resistance is a potential common link between these conditions, and it is associated with AD due to the insulin-degrading enzyme (IDE), which also degrades amyloid-β (Aβ) in the brain. READ MORE