Search for dissertations about: "O-antigen polysaccharide"

Showing result 1 - 5 of 10 swedish dissertations containing the words O-antigen polysaccharide.

  2. 1. Structure Elucidations of Bacterial Polysaccharides using NMR Spectroscopy and Bioinformatics

    Author : Jonas Ståhle; Göran Widmalm; Evgeny Vinogradov; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; Bioinformatics; NMR Spectroscopy; Lipopolysaccharide; Glycosyltransferase; Computer-Assisted Structure Elucidation; O-antigen; Biosynthesis; Organic Chemistry; organisk kemi;

    Abstract : Carbohydrates are ubiquitous components in nature involved in a range of tasks. They cover every cell and contribute both structural stability as well as identity. Lipopolysaccharides are the outermost exposed part of the bacterial cell wall and the primary target for host-pathogen recognition. READ MORE

  4. 2. NMR spectroscopy in structural and conformational analysis of bacterial polysaccharides

    Author : Carolina Fontana; Göran Widmalm; Sven Müller-Loennies; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nuclear Magnetic Resonance; carbohydrates; O-antigen polysaccharide; organisk kemi; Organic Chemistry;

    Abstract : Carbohydrates constitute one of the three major classes of biomolecules found in all living cells and, unlike nucleic acids and proteins, their polymeric structures are not based on a template. The structural diversity of these molecules confers them an enormous capacity to encode information in biological systems, acting as efficient mediators in the interaction of the cell with the environment. READ MORE

  5. 3. Complement-dependent defence against bacterial infection. Studies in C2 deficiency

    Author : Barbro Selander; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody responses; polysaccharide antigens; vaccination; mannan-binding lectin MBL ; complement; C2 deficiency; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : The complement system is critically involved in defence against bacterial infection. C2 deficiency is, apart from mannan-binding lectin (MBL) deficiency, the most common homozygous complement deficiency among Caucasians. READ MORE

  6. 4. Structural studies of some bacterial polysaccharides and extension of a method for lipid A cleavage

    Author : Reine Eserstam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Serratia marcescens; Hafnia alvei; Vibrio cholerae; polysaccharide; NMR;

    Abstract : The focus of the work presented in this thesis has been to study the structures of the capsular polysaccharide from Serratia marcescens O14:K12, and the O-antigen polysaccharides from Hafnia alvei strain 10457 and Vibrio cholerae serogroup 037. Nuclear magnetic resonance (NMR) spectroscopy was the primary technique employed. S. READ MORE

  7. 5. Structural studies of bacterial carbohydrate antigens with focus on oral commensal bacteria

    Author : Niklas Bergström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Streptococcus mitis; Streptococcus pneumoniae; Vibrio cholerae; polysaccharide; structure; Nuclear magnetic resonance spectroscopy NMR ; Mass spectrometry MS .;

    Abstract : 90% of the total number of cells in the human body consist of the normal bacterial flora. These bacteria are mostly not harmful and, indeed, even beneficial as long as they remain physiologically outside the body, e.g., within the gastro-intestinal tract. READ MORE