Search for dissertations about: "OPLS"

Showing result 21 - 25 of 37 swedish dissertations containing the word OPLS.

  2. 21. Computerized tools : a substitute or a supplement when diagnosing Alzheimer's disease?

    Author : Carlos Alberto Aguilar Palomeque; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer’s disease (AD) is the most common form of dementia in the elderly characterized by difficulties in memory, disturbances in language, changes in behavior, and impairments in daily life activities. By the time cognitive impairment manifests, substantial synaptic and neuronal degeneration has already occurred. READ MORE

  4. 22. Development and Application of Computational Methods in Antitubercular Drug Design : Identification of Novel Inhibitors of Ribonucleotide Reductase

    Author : Daniel Muthas; Anders Karlén; Anders Hallberg; Johan Gottfries; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Medicinal Chemistry; läkemedelskemi;

    Abstract : Tuberculosis kills approximately 1.7 million people each year around the world making it one of the most lethal infectious diseases. This thesis concerns the development of two computational tools that can support the early stages of drug discovery, and their use in an anti-tubercular drug discovery program. READ MORE

  5. 23. On Biogenic Halocarbons in Antarctic Waters

    Author : Erik Mattsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Volatile biogenic halocarbons; Antarctica; Southern Ocean; Sea ice; Snow; Air-sea exchange;

    Abstract : Little is known regarding the distribution of naturally produced volatile halogenated organic compounds, halocarbons, in Antarctic waters and the contribution of these waters to the global atmospheric load of halogens. In the atmosphere, halocarbons are degraded by photolysis, and form reactive halogen radicals. READ MORE

  6. 24. Association of hydrophobic organic compounds to organic material in the soil system

    Author : Silviu-Laurentiu Badea; Mats Tysklind; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HOCs; Organic Matter; Clay; DOM; Environmental Science; miljövetenskap;

    Abstract : Contaminated soils and sediments have been identified as significant secondary sources of organic contaminants.  Leaching tests may be useful tools to estimate the mobility of contaminants via the water phase and thereby the risk for groundwater and surface water contamination. READ MORE

  7. 25. Smoking and human airway inflammatory cells : studies with focus on T cells in the development of COPD

    Author : Helena Forsslund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic obstructive pulmonary disease (COPD), the fourth leading cause of death worldwide, is characterized by persistent airflow limitation and a chronic inflammation of the lungs. One of the major risk factors is long-term exposure to cigarette smoking. READ MORE