Advanced search

Showing result 1 - 5 of 9 swedish dissertations matching the above criteria.

2. 1. Animal genomics – gene discovery and gene characterization

   Author : Rakan Naboulsi; Leif Andersson; Mårten Larsson; Susanne Kerje; Tosso Leeb; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Spontaneous autoimmune thyroiditis; SAT; Hashimoto’s thyroiditis; HT; Obese strain; transcriptional regulation; ZBED6; Igf2; miRNA; miR483; Whole-genome sequencing; RNA-seq; miRNA-seq;

   Abstract : This thesis involves two projects. The aim in the first project was to identify genomic regions associated with spontaneous autoimmune thyroiditis (SAT), which is a hereditary autoimmune disease that affects the obese strain (OS) of chicken, an animal model for human Hashimoto’s thyroiditis (HT). READ MORE

4. 2. Calibration and Modelling of Adipose Tissue Under Impact Loading

   Author : Hosein Naseri; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Constitutive modelling; Global sensitivity analysis; Adipose tissue; Finite element human body models; Obesity;

   Abstract : Vehicular injury is one of the main reasons for traumatic injuries. Finite Element HumanBody Models (FEHBM) have become very popular to assess car crashes and the subsequentinjuries. It provides the possibility to predict stress and strain values in tissue level byrepresenting anatomical structures in details. READ MORE

5. 3. Material Modelling of Adipose Tissue for Traffic Injury Prevention

   Author : Hosein Naseri; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Finite element human body models; Global sensitivity analysis; Obesity; Adipose tissue; Constitutive modelling; Submarining;

   Abstract : Traffic injury is one of the main reasons for traumatic injuries. Obese occupants are among the vulnerable populations with a higher risk of death and severe injuries. Notably, obesity is associated with a thick layer of subcutaneous adipose (fat) tissue. READ MORE

6. 4. Lifestyle and infections : an epidemiological approach on the role of obesity, physical activity, sleep and stress

   Author : Francesca Ghilotti; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The immune system plays a fundamental role in defending the human body from external pathogens. Some individuals, however, have a weaker immune system leading to more frequent infections. Infections are associated with high burden to society, both in terms of economic costs and morbidity. READ MORE

7. 5. Genetic Characterization of Chicken Models for Autoimmune Disease

   Author : Anna-Stina Sahlqvist; Olov Ekwall; Olle Kämpe; Leif Andersson; Susanne Kerje; Holger Luthman; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Autoimmune disease; Hashimoto’s thyroiditis; systemic sclerosis; comparative genomics; linkage analysis; OS chickens; spontaneous autoimmune thyroiditis; UCD-200 chickens.; Molekylär medicin; Molecular Medicine;

   Abstract : Autoimmune diseases are endemic, but the disease mechanisms are poorly understood. A way to better understand these are to find disease-regulating genes. However, this is difficult as the diseases are complex, with several genes as well as environmental factors influencing the development of disease. READ MORE