Search for dissertations about: "Obese strain"

Showing result 6 - 9 of 9 swedish dissertations containing the words Obese strain.

2. 6. Neuro-immune communication: role of the vagus nerve : an electrophysiological study

   Author : Violeta Bucinskaite; Karolinska Institutet; Karolinska Institutet; []
   Keywords : cholecystokinin; CCKA; CCKB; cytokines; IL-1[beta]; illness; nerve activity; NIDDM; OLETF; the vagus; vagotomy;

   Abstract : Defence mechanisms involve close interactions between the nervous and immune systems following an immune challenge. The vagal pathways which modulate major visceral functions under normal conditions are also important neural pathways for the transmission of information on peripheral conditions to the CNS. READ MORE

4. 7. Functional studies of candidate genes contributing to type 1 diabetes in the NOD mouse

   Author : Marie Lundholm; Dan Holmberg; Vivianne Malmström; Umeå universitet; []
   Keywords : Type 1 Diabetes; NOD mouse; CTLA-4; Ctex; CD3ζ; apoptosis; Idd6; Lrmp; medicinsk genetik; Medical Genetics;

   Abstract : Type 1 Diabetes (T1D) is an autoimmune disorder caused by both genetic and environmental factors. The non-obese diabetic (NOD) mouse is one of the best and most commonly studied animal models for T1D. This mouse strain spontaneously develops diabetes through a process that closely resembles the human pathogenesis. READ MORE

5. 8. Imaging the pancreas : new aspects on lobular development and adult constitution

   Author : Andreas Hörnblad; Ulf Ahlgren; Guy Rutter; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; ß-cell mass; tertiary lymphoid organs; biomedical imaging; optical projection tomography; morphogenesis; pancreas development; gastric lobe; spleen development.; medicinsk genetik; Medical Genetics; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

   Abstract : The mouse pancreas is a mixed exocrine and endocrine glandconsisting of three lobular compartments: the splenic, duodenal and gastric lobes. During embryogenesis, the pancreas forms from two progenitor populations located on the dorsal and ventral side of the primitive gut tube. READ MORE

6. 9. Osteoarthritis. Epidemiologic and genetic aspects

   Author : Jonas Franklin; Lund Ortopedi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; body mass index; knee; hip; epidemiology; Osteoarthritis; occupation; hip fracture; inheritance; natural history;

   Abstract : The purpose of this study was to (I) assess the association between body mass index (BMI) and total hip replacement (THR) and total knee replacement (TKR) due to osteoarthritis (OA), (II) assess the association between the mechanical load of work and THR and TKR due to OA, (III) evaluate the natural history of radiographic hip OA with regards to THR and hip fracture, (IV) to determine the prevalence of radiographic OA in patients with hip fracture, and (V) to examine and compare the inheritance patterns of THR for OA and hip fracture. OA was previously regarded as a consequence of the wear and tear the joint is subjected to during one’s lifetime. READ MORE