Search for dissertations about: "Obesity-associated inflammation in adipose tissue"

Showing result 1 - 5 of 6 swedish dissertations containing the words Obesity-associated inflammation in adipose tissue.

  2. 1. Obesity-associated inflammation in adipose tissue

    Author : Malin Alvehus; Tommy Olsson; Agneta Holmäng; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; inflammation; pro-inflammatory cytokines; serum; obesity; weight loss; menopause;

    Abstract : Background: Excess body fat, particularly in the visceral depot, is linked to increased mortality and morbidity, including the development of diseases such as type 2 diabetes, cardiovascular disease, and cancer. Chronic low-grade inflammation in adipose tissue may be a key mediator of obesity-associated diseases. READ MORE

  4. 2. Angiogenic mechanims in adipose tissue and tumor

    Author : Sharon Siew Hoon Lim; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Angiogenesis is involved in the development and progression of many human diseases, including cancer, cardiovascular diseases, chronic inflammation, and metabolic diseases. Despite differences in microenvironment under various pathological settings, angiogenic blood vessels share some common features in numerous diseases. READ MORE

  5. 3. Studies on novel interactors in human adipose tissue

    Author : Amanda T Pettersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity is associated with a mild inflammation and altered protein secretion in adipose tissue. These changes have been suggested to contribute to the development of obesity-associated disorders including, insulin resistance, dyslipidemia, type 2 diabetes and cardiovascular disease. READ MORE

  6. 4. Immune cell-derived adipokines : role in white adipose tissue function and link to metabolic health

    Author : Kaisa Hofwimmer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The white adipose tissue (WAT) is home to a vast array of immune cells that control local homeostasis and metabolism by engaging in intricate crosstalk with adipocytes and their precursors through secreted factors (adipokines). In the obese WAT, these immune cells adopt a pro-inflammatory profile, resulting in a state of chronic low-grade inflammation that can perturb local and systemic metabolic function. READ MORE

  7. 5. Role of immune mediators in metabolic syndrome and atherosclerosis

    Author : Daniela Strodthoff; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity is increasingly becoming a problem worldwide. Both location and metabolic activity of visceral and subcutaneous white adipose tissue (WAT) differ. Visceral fat is highly vascularized resulting in increased blood supply and increased infiltration of inflammatory immune cells such as macrophages, T cells and even B cells. READ MORE