Search for dissertations about: "Observational study drug"

Showing result 1 - 5 of 55 swedish dissertations containing the words Observational study drug.

2. 1. Pharmacoepidemiologic Studies of Diabetes Mellitus - with special reference to - Glucose Control and Prognosis of Type 2 Diabetes

   Author : Jonny Olsson; Samhällsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; cohort study; longitudinal study; cross-sectional study; mortality; diabetes mellitus; Pharmacoepidemiology; prevalence; type 2 diabetes; diabetes costs; short-term sick-leave; premature retirement; production losses; inpatient care; glycaemic control; fasting blood glucose; oral antihyperglycaemic agents; sulphonylurea; metformin; insulin; combination treatment; drug utilization; prescribed daily doses; safety; effectiveness; Endokrinologi; sekretion; diabetologi;

   Abstract : The efficacy and safety of antihyperglycaemic drugs have been evaluated in one American and one British randomized clinical trial, which have given contradictory results. The positive results of the latter may be more convincing as it included a greater number of patients and as its duration was longer. READ MORE

4. 2. Design and analysis with observational data : Protocols and modeling with the aim of causal inference

   Author : Paulina Jonéus; Mattias Nordin; Per Johansson; Jenny Häggström; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; observational studies; protocols guidelines; epidemiology; public health; prostate disease; Statistics; Statistik;

   Abstract : This thesis consists of six papers that study the design and analysis with observational data.There is a growing interest in using real-world evidence (RWE) for regulatory purposes. The belief is that observational data can make drug developmentmore efficient and speed up patient access to new drugs. READ MORE

5. 3. Sex and gender aspects in drug utilization

   Author : Desirée Loikas; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Drug prescribing is one of the most important processes in healthcare and drugs are also commonly used in the population. Drug use differs between men and women and descriptive reports of sex differences in drug use have been published with examples from different therapeutic areas. READ MORE

6. 4. Observational and experimental studies of drug treatment of infection and myocardial infarction/depression in a hospital in St. Petersburg

   Author : Ksenia Goryachkina; Karolinska Institutet; Karolinska Institutet; []
   Keywords : St Petersburg; hospital; routine drug use; epidemiological studies; experimental studies; myocardial infarction; metoprolol; paroxetine; CYP2D6; antibiotics; microbial resistance; drug interaction; drug utilization;

   Abstract : Introduction: Treatment of infectious and cardiac diseases represents subjects of great concern for health care all over the world, e.g. in Russia. Major problems may occur in routine use of the drugs that need to be timely considered. READ MORE

7. 5. Drug use in the elderly : are quantity and quality compatible

   Author : Inga Klarin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Population-based; cross-sectional; longitudinal; aged; aged 80 and over; drug utilization; cardiovascular agents; angiotensin-converting enzyme inhibitors; inappropriate drug use; heart failure; dementia; hospitalization; mortality; Sweden.;

   Abstract : The increasing number of elderly, and the increasing drug use among the elderly, emphasizes the need to continuously monitor drug utilization in this group. The scarcity of randomized controlled trials including elderly people give population-based, observational studies an important role as source of information on drug use and drug-related problems. READ MORE