Search for dissertations about: "Observational study"

Showing result 1 - 5 of 346 swedish dissertations containing the words Observational study.

  1. 1. Genetic Determinants of Dyslipidemia

    University dissertation from Lund University, Faculty of Medicine

    Author : Tibor V Varga; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetic epidemiology; Genetic polymorphism; dyslipidaemia; Cholesterol; Triglyceride; Genetic risk; genetic risk score; Single nucleotide polymorphism; Prediction; Gene-environment interactions; Randomized controlled trial; prospective cohort studies; Observational study; GLACIER Study; Diabetes Prevention Program;

    Abstract : Dyslipidemia is a chronic deviation from normal blood lipid levels that can lead to atherosclerosis and other cardiovascular diseases; dyslipidemia and its sequelae are caused by the complex interplay of genetic and environmental factors. Although circulating concentrations of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (LDL-C) have a strong genetic underpinning, not much is known about the genetic factors that affect long-term deteriorations in lipid concentrations. READ MORE

  2. 2. Pharmacoepidemiologic Studies of Diabetes Mellitus - with special reference to - Glucose Control and Prognosis of Type 2 Diabetes

    University dissertation from Jonny Olsson, Department of Community Medicine, Malmö University Hospital, SE-205 02 MALMÖ, Sweden

    Author : Jonny Olsson; Lunds universitet.; Lund University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; cohort study; longitudinal study; cross-sectional study; mortality; diabetes mellitus; Pharmacoepidemiology; prevalence; type 2 diabetes; diabetes costs; short-term sick-leave; premature retirement; production losses; inpatient care; glycaemic control; fasting blood glucose; oral antihyperglycaemic agents; sulphonylurea; metformin; insulin; combination treatment; drug utilization; prescribed daily doses; safety; effectiveness; Endokrinologi; sekretion; diabetologi;

    Abstract : Popular Abstract in Swedish Läkemedel blir allt viktigare behandlings-instrument och kunskapen ökar om läke-medels verkningsmekanismer. Även om denna kunskap kombineras med resultat från kliniska läkemedelsprövningar är detta dock inte tillräckligt för att värdera kliniska fördelar och risker med en rutinmässig läkemedels-behandling, särskilt inte om behandlingen är långvarig. READ MORE

  3. 3. Methods for improving covariate balance in observational studies

    University dissertation from Umeå : Umeå universitet

    Author : Philip Fowler; Umeå universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; causal effect; coarsening; discretisation; proxy variables; register study; swedish social insurance agency; unobserved variables;

    Abstract : This thesis contributes to the field of causal inference, where the main interest is to estimate the effect of a treatment on some outcome. At its core, causal inference is an exercise in controlling for imbalance (differences) in covariate distributions between the treated and the controls, as such imbalances otherwise can bias estimates of causal effects. READ MORE

  4. 4. Observational Uncertainties in Water-Resources Modelling in Central America Methods for Uncertainty Estimation and Model Evaluation

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ida Westerberg; Uppsala universitet.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Central America; Discharge; Flow-duration curve; Fuzzy regression; GLUE; Model evaluation; Non-stationarity; Observational uncertainty; Precipitation; Quality control; Rating curve; Regionalisation; Uncertainty estimation; Ungauged basins; Water resources; Avbördningskurva; Centralamerika; GLUE; icke-stationaritet; kvalitetskontroll; modellutvärdering; nederbörd; observationsosäkerheter; avrinningsområden utan vattenfö-ringsdata; oskarp regression; osäkerhetsuppskattning; regionalisering; varaktighetskurva; vattenföring; vattenresurser; NATURAL SCIENCES Earth sciences Atmosphere and hydrosphere sciences Hydrology; NATURVETENSKAP Geovetenskap Atmosfärs- och hydrosfärsvetenskap Hydrologi; Hydrology; Hydrologi;

    Abstract : Knowledge about spatial and temporal variability of hydrological processes is central for sustainable water-resources management, and such knowledge is created from observational data. Hydrologic models are necessary for prediction for time periods and areas lacking data, but are affected by observational uncertainties. READ MORE

  5. 5. An Observational Study of Accretion Processes in T Tauri Stars

    University dissertation from Uppsala : Institutionen för astronomi och rymdfysik

    Author : Henricus Cornelis Stempels; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Astronomy; Star formation; T Tauri stars; Emission lines; Accretion; NLTE radiative transfer; Astronomi; NATURAL SCIENCES Physics Astronomy and astrophysics; NATURVETENSKAP Fysik Astronomi och astrofysik; Astronomy; Astronomi;

    Abstract : This thesis is a detailed observational study of the accretion processes in T Tauri stars (TTS). The interaction between the central star, the circumstellar disk and the magnetic field gives rise to a wide range of features in the spectra of TTS. READ MORE