Search for dissertations about: "Oligonucleotide-peptide conjugates"

Found 1 swedish dissertation containing the words Oligonucleotide-peptide conjugates.

2. 1. Development of a novel methodology for the synthesis of oligonucleo-peptide conjugates

   Author : Simone Zaramella; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Antisense; Oligonucleotide-peptide conjugates; Solid-phase synthesis; Histidine; Protecting groups.;

   Abstract : Peptide-oligonucleotide conjugates constitute a new class of antisense molecules that exhibit improved biological activity over standard oligonucleotide analogues. Currently, these oligomeric bioconjugates are prepared by either solution- or solid-phase techniques. READ MORE