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Showing result 1 - 5 of 25 swedish dissertations matching the above criteria.

2. 1. Xenotransplantation of fetal porcine islet-like cell clusters in diabetes mellitus : an experimental and clinical study

   Author : Olle Korsgren; Uppsala universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : .... READ MORE

4. 2. Preparatory Studies to Introduce Regulatory T Cells in Clinical Transplantation

   Author : David Berglund; Gunnar Tufveson; Olle Korsgren; David Sachs; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplantation; Tolerance; Cell therapy; Regulatory T cell; In vivo imaging; Cell purification;

   Abstract : Solid organ transplantation has evolved from being an experimental procedure to a life-saving treatment for patients with end-stage organ failure. The risk of losing a transplant due to acute rejection is very low with the use of modern immunosuppressive protocols and the short-term results are impressive. READ MORE

5. 3. Studies of Regulatory T cells with Implications for Clinical Applications

   Author : Marcus Bergström; Olle Korsgren; Wayne Hawthorn; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regulatory T cell; Treg; Transplantation; Immunology; Tolerance; Islet transplantation; Immunosuppression; Immunologi; Immunology;

   Abstract : Regulatory T cells (Tregs) are vital for regulating immune homeostasis and for preventing immunopathology. The immunosuppressive functions of Tregs have raised hope for their potential use in clinical applications. READ MORE

6. 4. Islet Transplantation a Technical Challenge : Studies on Human Pancreas Preservation and Enzymatic Digestion

   Author : José Caballero-Corbalán; Olle Korsgren; Daniel Brandhorst; Ralf Segersvärd; Federico Bertuzzi; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet transplantation; Human islet isolation; Pancreas preservation; Two-layer method; Perfluorocarbon; Cold storage; Cold ischemia; University of Wisconsin solution; Histidine-tryptophan-ketoglutarate; HTK; Pancreas preservation; Prediction; Collagenase; Trasplante de islotes; Aislamiento de islotes; Preservación del pancreas; Método de las dos capas; Colagenasa; Solución de Wisconsin; HTK; Histidina-triptófano-ketoglutarato; Predicción; Endocrinology; Endokrinologi; Transplantation surgery; Transplantationskirurgi; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Cellforskning; Cell Research; Klinisk immunologi; Clinical Immunology;

   Abstract : Islet transplantation has found its niche in diabetes treatment. It has contributed to a better quality of life and better glycemic control of patients with diabetes suffering from severe hypoglycemia that are not eligible for vascularized pancreas transplantation. Islet isolation is a technically challenging procedure. READ MORE

7. 5. Pancreatic Islet Transplantation : Modifications of Islet Properties to Improve Graft Survival

   Author : Sanja Cabric; Olle Korsgren; Bo Nilsson; Peetra Magnusson; Michael Breimer; Uppsala universitet; []
   Keywords : Medicine; Diabetes; islet transplantation; islets of Langerhans; coagulation activation; IBMIR; hirudin; heparin; growth factor; angiogenesis; Medicin;

   Abstract : During the past decade clinical islet transplantation has become a viable strategy for curing type 1 diabetes. The limited supply of organs, together with the requirement for islets from multiple donors to achieve insulin independence, has greatly limited the application of this approach. READ MORE