Search for dissertations about: "One-Pot Synthesis"
Showing result 11 - 15 of 66 swedish dissertations containing the words One-Pot Synthesis.
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11. GALIELLALACTONE ANALOGUES – SYNTHESIS AND PROPERTIES
Abstract : Cancer cells use normal cell signalling pathways in a proliferative fashion in order to prolong their own survival. Inhibition of one of the major signal proteins, STAT3 (Signal Transducer and Activator of Transcription 3) has previously been shown to induce apoptosis. READ MORE
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12. Metallocene based peptidomimetics and chiral catalysts
Abstract : Several optically active organometallic Phe-AAn-Phe peptidomimetics and macrocyclic Phe-(Phe)n peptides have been synthesized by either intra- or intermolecular peptide bond formation of the corresponding bis(amino acid) derivatives. The key bis(amino acid) derivatives were available from an improved multi-step synthetic route, utilising Horner-Wadswort-Emmons olefination of organometallic aldehydes with phosphonylglycine reagents, enantioselective hydrogenation of didehydro amino acids and classical solution and/or solid phase peptide synthesis methodology. READ MORE
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13. Lanthanide Metal-Organic Frameworks and Hierarchical Porous Zeolitic Imidazolate Frameworks : Synthesis, Properties, and Applications
Abstract : This thesis presents the synthesis, properties, and applications of two important classes of metal-organic frameworks (MOFs); lanthanide MOFs and hierarchical porous zeolitic imidazolate frameworks (ZIFs). The materials have been characterized using a wide range of techniques including diffraction, imaging, various spectroscopic techniques, gas sorption, dynamical light scattering (DLS) and thermogravimetric analysis (TGA). READ MORE
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14. Reaction Between Grignard reagents and Heterocyclic N-oxides : Synthesis of Substituted Pyridines, Piperidines and Piperazines
Abstract : This thesis describes the development of new synthetic methodologies for preparation of bioactive interesting compounds, e.g. substituted pyridines, piperidines or piparazines. Thesecompounds are synthesized from commercially available, cheap and easily prepared reagents, videlicet the reaction between Grignard reagents and heterocyclic N-oxides. READ MORE
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15. Amino acid-catalyzed synthesis of amino acid derivatives : Application and semi-synthesis of Paclitaxel, Docetaxel and their derivatives
Abstract : This thesis deals with different applications of organocatalysis, where amino acid derivatives and small peptides are applied as catalysts. First, the development of environmentally friendly aldol reactions, carried out in aqueous media is illustrated. The corresponding β-hydroxy ketones are formed with ee´s up to 99%. READ MORE
