Search for dissertations about: "Op18 Stathmin"

Found 2 swedish dissertations containing the words Op18 Stathmin.

  1. 1. Molecular dissection of established and proposed members of the Op18/Stathmin family of tubulin binding proteins

    Author : Kristoffer Brännström; Martin Gullberg; Fredrik Ivars; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Op18 Stathmin; Sm16; tubulin; microtubule; schistosoma mansoni; Molecular biology; Molekylärbiologi;

    Abstract : My initial aim was a functional analysis of the conserved Op18/stathmin family of microtubule-regulators, which includes the ubiquitous cytosolic Op18 protein and the neural membrane-attached RB3 and SCG10 proteins. The solved X-ray structure has shown that these proteins form a complex with tubulin -heterodimers via two imperfect helical repeats, which result in two head-to-tail aligned heterodimers in a tandem-tubulin complex. READ MORE

  2. 2. Cytoskeletal filament systems : assembly, regulation, and interplay in mammalian cells

    Author : Mikael E Sellin; Martin Gullberg; Jeremy Thorner; Mikael E. Sellin; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell research; cellforskning;

    Abstract : The cell represents the basic unit of structure and function for all life. The interior of a eukaryotic cell is organized by an extensive array of protein filaments – collectively referred to as the cytoskeleton. These filaments serve diverse essential functions, e.g. READ MORE