Search for dissertations about: "Open lung approach"

Showing result 1 - 5 of 12 swedish dissertations containing the words Open lung approach.

  2. 1. Pathophysiological and Histomorphological Effects of One-Lung Ventilation in the Porcine Lung

    Author : Alf Kozian; Göran Hedenstierna; Thomas Hachenberg; Filip Freden; Sten Walther; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alveolar Recruitment Manoeuvre; One-Lung Ventilation; Lung Protective Ventilation; Tidal Volume; Computed Tomography; Tidal Recruitment; Animal Model; Open Thoracic Surgery; Ventilation Perfusion Distribution; Single Photon Emission Computed Tomography; Diffuse Alveolar Damage; Medical laboratory science; Medicinsk laboratorievetenskap; Anestesiologi; Anaesthesiology;

    Abstract : Thoracic surgical procedures require partial or complete airway separation and the opportunity to exclude one lung from ventilation (one-lung ventilation, OLV). OLV is commonly associated with profound pathophysiological changes that may affect the postoperative outcome. READ MORE

  4. 2. Hemodynamic Effects of Lung Function Optimization in Experimental Acute Respiratory Distress Syndrome

    Author : Arnoldo Santos; Anders Larsson; Fernando Suarez-Sipmann; John Marini; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute respiratory distress syndrome; Lung protective ventilation; Mechanical ventilation; Open lung approach; Pulmonary heart disease; Pulmonary vascular mechanics; Pulmonary vascular dysfunction; Pulse wave analysis; Right ventricular dysfunction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Fysiologi; Physiology;

    Abstract : Acute Respiratory Distress Syndrome (ARDS) is a severe pulmonary inflammation affecting thousands of patients every year in Sweden and has a mortality of 30-50%. Mechanical ventilation (MV) is usually necessary, but could per se augment the inflammation and contribute to mortality. READ MORE

  5. 3. Airway pressure release ventilation : A systematic experimental approach

    Author : Peter Neumann; Uppsala universitet; []
    Keywords : Medical sciences; APRV; CPAP; atelectasis; recruitment; PEEP; inverse ratio ventilation; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Physiology; klinisk fysiologi;

    Abstract : Airway pressure release ventilation (APRV) is a ventilatory mode which allows unrestrictedspontaneous breathing (SB) throughout the ventilatory cycle. If SB is insufficient, mechanicalventilatory support is achieved by brief periodic decreases of the airway pressure below the CPAPlevel. READ MORE

  6. 4. Immunopeptidomics and autoantigens of interstitial lung diseases

    Author : Emil Wiklundh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : We investigate Sarcoidosis and Idiopathic Pulmonary Fibrosis, IPF, to find markers for early fibrosis development. The aetiologies for both diseases are unknown and there is no specific treatment, moreover, there is a lack of diagnostic biomarkers for both diagnose and disease activity. READ MORE

  7. 5. Regional Lung Kinetics of Ventilator-Induced Lung Injury and Protective-Ventilation Strategies Studied by Dynamic Positron Emission Tomography

    Author : João Batista Borges; Anders Larsson; Giacomo Bellani; Uppsala universitet; []
    Keywords : [18F]fluoro-2-deoxy-D-glucose; positron emission tomography; acute pulmonary inflammation; acute respiratory distress syndrome; mechanical ventilation; ventilator-induced lung injury;

    Abstract : Mechanical ventilation in itself can harm the lung and cause ventilator-induced lung injury (VILI), which can induce or aggravate acute respiratory distress syndrome (ARDS). Much debate remains over pivotal concepts regarding the pathophysiology of VILI, especially about the precise contribution, kinetics, and primary role of potential VILI mechanisms. READ MORE