Search for dissertations about: "Opiate"

Showing result 1 - 5 of 22 swedish dissertations containing the word Opiate.

  2. 1. Enterostatin - target proteins and intracellular mechanisms. Function in food intake and energy metabolism

    Author : Karin Berger; Molekylär endokrinologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; energy metabolism; insulin; uncoupling protein; beta-casomorphin; opiate; SK-N-MC; INS-1; Medicin människa och djur ; Medicine human and vertebrates ; fat intake; F1F0-ATP synthase; appetite; enterostatin; satiety; obesity;

    Abstract : Hunger and satiety are the results of complex neural events that involve several neurotransmitters and peptides. Enterostatin is an appetite-regulating peptide released in the intestine in response to fat ingestion. Enterostatin specifically decreases fat intake, but has also metabolic effects like inhibition of insulin secretion. READ MORE

  4. 2. Toxicological studies of opiate-related death

    Author : Joakim Strandberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis comprises studies on opiate overdose death, and focuses on evaluation of toxicological characteristics including the possible influence of abstinence and polydrug use for the fatal outcome. In order to identify and classify drug abusers, a screening method for several drugs of abuse was developed and applied on randomly selected autopsy cases. READ MORE

  5. 3. Mechanisms of opiate tolerance and dependence in the rat

    Author : Orsolya Hoffman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Drug addiction is a complex phenomenon with various biological, psychological and social causes and consequences, which belongs to the major problems of today's society. Opiates have been used and misused for thousand of years and addiction to them develops both in humans and in animals. READ MORE

  6. 4. In vitro and postmortem studies of the brain opioid system : association to opiate dependence

    Author : Parisa Zarnegar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Opioid system; brain; gene expression; amygdala; hippocampus; opiate dependence;

    Abstract : Opioids such as heroin are highly addictive illicit drugs. The μ opioid receptor (MOR) plays a central role in mediating the effects of opiates and related opioid. READ MORE

  7. 5. Hepatitis C virus infection in patients receiving opiate substitution therapy in Sweden

    Author : Anna Jerkeman; Enheten för infektionssjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The hepatitis C virus (HCV) is a blood borne virus effectively spread through injection practices. Consequently, people who inject drugs (PWID) are at the center of the current HCV epidemic in industrialized countries, with regards both to prevalence and incidence. READ MORE