Search for dissertations about: "Opioids"

Showing result 6 - 10 of 103 swedish dissertations containing the word Opioids.

  2. 6. The Impact of Growth Hormone and Gamma-Hydroxybutyrate (GHB) on Systems Related to Cognition

    Author : Jenny Johansson; Mathias Hallberg; Fred Nyberg; Linda Fryklund; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth Hormone; Gamma-Hydroxybutyrate; GABAB; Opioids; Insulin-like growth factor 1; Rats; Central Nervous System; Autoradiography; Radioimmunoassay; ELISA; Water Maze; Open Field; Biological Research on Drug Dependence; Biologisk beroendeforskning;

    Abstract : Drug dependence is a serious and increasing problem in our society, especially among adolescents. The use of the large variety of substances available can result in a range of physiological and psychological adverse effects on individuals and negative consequences on the society overall. READ MORE

  4. 7. Opioids and regulation of breathing

    Author : Åsa Österlund Modalen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sameridine; partial - opioid agonist; local anesthetic; morphine; ventilation; respiratory depression; hypercarbia; hypoxia; frakefamide; peripheral -opioid agonist;

    Abstract : A most important challenge even in modern medicine is effective treatment of pain. Respiratory depression is the most feared side effect of analgesic treatment in the clinical situation. READ MORE

  5. 8. Growth Hormone and Anabolic Androgenic Steroids : Effects on Neurochemistry and Cognition

    Author : Alfhild Grönbladh; Mathias Hallberg; Jörgen Isgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; anabolic androgenic steroids; nandrolone decanoate; insulin-like growth factor; GABAB; opioids; memory; water maze; autoradiography; central nervous system; rats; Biological Research on Drug Dependence; Biologisk beroendeforskning;

    Abstract : Growth hormone (GH) stimulates growth and metabolism but also displays profound effects on the central nervous system (CNS). GH affects neurogenesis and neuroprotection, and has been shown to counteract drug-induced apoptosis in the brain. READ MORE

  6. 9. Anabolic Androgenic Steroids : Effects on Neuropeptide Systems in the Rat Brain

    Author : Mathias Hallberg; Fred Nyberg; Pierre Le Grevès; James Zadina; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Anabolic androgenic steroids; Nandrolone decanoate; Substance P; NK1 receptor; Substance P 1-7 ; Endopeptidase; Opioids; Calcitonin gene-related peptide; Radioimmunoassay; Autoradiography; Central nervous system; Rats; Biologisk beroendeforskning; Biological research on drug dependence; Biologisk beroendeforskning;

    Abstract : Anabolic-androgenic steroids (AAS) have been used in clinics for decades. The misuse of AAS has previously been attributed merely to sport athletes, taking AAS with intentions to increase muscle mass, enhance physical performance and to improve results in competitions. READ MORE

  7. 10. Bariatric Surgery : Outcomes after Gastric Bypass and Duodenal Switch

    Author : Martin Löfling Skogar; Magnus Sundbom; Ville Wallenius; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Body composition; fat-free mass; resting metabolic rate; bariatric surgery; obesity; Roux-en-Y Gastric Bypass; Duodenal Switch; air-displacement plethysmography; Bod Pod; indirect calorimetry assessment; BAROS; quality of life; weight loss; diabetes; hypertension; dyslipidmia; depression; pain; antidepressants; opioids; complications; healthcare consumption; adverse events; Surgery; Kirurgi;

    Abstract : Obesity is associated with increased morbidity and mortality. A BMI >40 kg/m2 shortens life expectancy by about 10 years. The obesity related comorbidities diabetes, hypertension, dyslipidemia and sleep apnea contributes to the increased risk of cardiovascular events. There is also an increased risk of some forms of cancer (e. READ MORE