Search for dissertations about: "Optimality Criterion"

Showing result 1 - 5 of 22 swedish dissertations containing the words Optimality Criterion.

  1. 1. Applied Adaptive Optimal Design and Novel Optimization Algorithms for Practical Use

    Author : Eric Strömberg; Andrew Hooker; Mats Karlsson; Timothy Waterhouse; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nonlinear Mixed Effects Models; Pharmacometrics; Fisher Information Matrix; Approximation; Optimality Criterion; Parallelization; Model Based Adaptive Optimal Design; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : The costs of developing new pharmaceuticals have increased dramatically during the past decades. Contributing to these increased expenses are the increasingly extensive and more complex clinical trials required to generate sufficient evidence regarding the safety and efficacy of the drugs. READ MORE

  2. 2. Multivariate Aspects of Phylogenetic Comparative Methods

    Author : Krzysztof Bartoszek; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; General Linear Model; Ornstein-Uhlenbeck process; Multivariate phylogenetic comparative method; Evolutionary model; Adaptation; Optimality; Measurement error; Regression; Adaptation; Major-axis regression; Reduced major-axis regression; Structural equation; Allometry; Phylogenetic inertia; Allometry;

    Abstract : his thesis concerns multivariate phylogenetic comparative methods. We investigate two aspects of them. The first is the bias caused by measurement error in regression studies of comparative data. We calculate the formula for the bias and show how to correct for it. READ MORE

  3. 3. Multicriteria optimization for managing tradeoffs in radiation therapy treatment planning

    Author : Rasmus Bokrantz; Anders Forsgren; Karl-Heinz Küfer; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Optimization; multicriteria optimization; robust optimization; Pareto optimality; Pareto surface approximation; Pareto surface navigation; intensity-modulated radiation therapy; volumetric-modulated arc therapy; intensity-modulated proton therapy; Optimering; flermålsoptimering; robust optimering; Paretooptimalitet; Paretofrontsapproximation; Paretofrontsnavigering; intensitetsmodulerad strålterapi; rotationsterapi; intensitetsmodulerad protonterapi;

    Abstract : Treatment planning for radiation therapy inherently involves tradeoffs, such as between tumor control and normal tissue sparing, between time-efficiency and dose quality, and between nominal plan quality and robustness. The purpose of this thesis is to develop methods that can facilitate decision making related to such tradeoffs. READ MORE

  4. 4. Optimization Algorithms for System Analysis and Identification

    Author : Ragnar Wallin; Alf Isaksson; Anders Hansson; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Optimization is a powerful and frequently used tool in many fields of research. In this thesis two relevant and important problems from robust control system analysis and system identification are solved using optimization algorithms. READ MORE

  5. 5. Optimal Control of Partial Differential Equations in Optimal Design

    Author : Jesper Carlsson; Anders Szepessy; Peter Hansbo; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Optimal design; Numerical analysis; Numerisk analys;

    Abstract : This thesis concerns the approximation of optimally controlled partial differential equations for inverse problems in optimal design. Important examples of such problems are optimal material design and parameter reconstruction. In optimal material design the goal is to construct a material that meets some optimality criterion, e.g. READ MORE