Search for dissertations about: "Optimization of tissue culture"

Showing result 1 - 5 of 8 swedish dissertations containing the words Optimization of tissue culture.

  2. 1. Development and optimization of a 3D in vitro model for osteogenic biomaterial evaluation

    Author : Luis Oliveros Anerillas; Peyman Kelk; Paul J. Kingham; Mikko Lammi; Jöns Hilborn; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; angiogenesis; biomaterial; bone marrow mesenchymal stem cells; bone regeneration; hydrogel; osteoinduction; osteogenesis; scaffold; type I collagen; 3D culture; biology; biologi; biomedical laboratory science; biomedicinsk laboratorievetenskap; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Despite the innate regenerative capabilities of bone tissue, self-repair is impaired when an injury exceeds the critical size threshold because of trauma, congenital, or pathological conditions. Autologous transplantation is the gold standard to reconstruct large bone defects. READ MORE

  4. 2. Digital Image Analysis of Cells : Applications in 2D, 3D and Time

    Author : Amalka Pinidiyaarachchi; Carolina Wählby; Ewert Bengtsson; Arvid Lundervold; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Digital image analysis; microscopy; fluorescent staining; watershed segmentation; sub-cellular localization; point-like signals; wavelets; cell confluence; cytology; color spaces.; Image analysis; Bildanalys;

    Abstract : Light microscopes are essential research tools in biology and medicine. Cell and tissue staining methods have improved immensely over the years and microscopes are now equipped with digital image acquisition capabilities. The image data produced require development of specialized analysis methods. READ MORE

  5. 3. Tissue engineering for novel female infertillity treatments: studies on small and large animal models

    Author : Arvind M. Padma; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rat; sheep; tissue engineering; decellularization; recellularization;

    Abstract : Introduction: As with any transplantation (Tx) procedure, uterus Tx is associated with risky donor surgery and adverse side-effects from immunosuppression. With the aim to bypass these risks, this thesis investigated uterus tissue engineering strategies and the potential to develop a patient-specific uterus graft to replace the need for donor surgery and immunosuppression. READ MORE

  6. 4. Regulation of human ovarian folliculogenesis in vitro

    Author : Inger Britt Carlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Culture; follicle; folliculogenesis; GDF-9; AMH; c-Kit Kit Ligand; matrix; oocyte; ovary; TGF-beta;

    Abstract : Cryopreservation of ovarian tissue containing immature oocytes is one approach to preserving the potential fertility of young women who risk losing their oocytes as a consequence of treatment with anti-cancer agents, or genetic disorders. This cryopreserved tissue can then be transplanted back into the ovary when the woman wants to have children. READ MORE

  7. 5. Pichia pastoris as a platform for the production of therapeutic glycoproteins

    Author : Magnus Sjöblom; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biokemisk processteknik; Biochemical Process Engineering;

    Abstract : Recombinant protein therapeutics is a growing market within the human medical biotechnology industry. The majority of all approved biopharmaceuticals are protein based and includes for example blood factors, anticoagulants, hormones, vaccine and monoclonal antibodies. READ MORE