Search for dissertations about: "Oral glucose tolerance tests"

Showing result 1 - 5 of 14 swedish dissertations containing the words Oral glucose tolerance tests.

  1. 1. Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus

    Author : Magnus Ekelund; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral glucose tolerance tests; Genetics; Autoimmunity; Insulin sensitivity; Gestational diabetes mellitus; Insulin secretion; HbA1c; Fasting glucose; FTO-gene; Postpartum diabetes;

    Abstract : The aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify possible markers and predictors for the development of manifest diabetes. The subjects were recruited through a regional screening programme in which oral glucose tolerance tests (OGTTs) are routinely offered to all pregnant women. READ MORE

  2. 2. Sampling from a suction induced mini-erosion in human skin. Methodological studies

    Author : Christer Svedman; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular permeability; neurogenic inflammation; glucose; diabetes mellitus; interstitial fluid; transdermal; skin; sampling; Medicine human and vertebrates ; Medicin människa och djur ;

    Abstract : Dermal interstitial fluid (IF) was extracted serially and painlessly by brief suction for as long as 6 days. The erosion was otherwise kept occluded, Sample volumes exceded those required for measuring a wide range of biological substances. Epidermal regeneration was rapid. READ MORE

  3. 3. Mechanism-Based Modelling of Clinical and Preclinical Studies of Glucose Homeostasis

    Author : Oskar Alskär; Maria C Kjellsson; Mats O Karlsson; Jenny Y. Chien; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucose homeostasis; pharmacometrics; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Abstract : Glucose is an important nutrient and energy source in the body. However, too high concentration in the blood is harmful and may lead to several complications developing over time. It was estimated that 5 million people in the world died from complications related to diabetes during 2015. READ MORE

  4. 4. Mechanism-Based Modeling of the Glucose-Insulin Regulation during Clinical Provocation Experiments

    Author : Petra Jauslin-Stetina; Mats Karlsson; Nicolas Frey; Philippe Jacqmin; Uppsala universitet; []
    Keywords : Pharmacokinetics Pharmacotherapy; Glucose homeostasis; Type 2 diabetes; IVGTT; OGTT; Meal test; Circadian variation; Mechanism-based; NONMEM; Farmakokinetik Farmakoterapi;

    Abstract : Type 2 diabetes is a complex chronic metabolic disorder characterized by hyperglycemia associated with a relative deficiency of insulin secretion and a reduced response of target tissues to insulin. Considerable efforts have been put into the development of models describing the glucose-insulin system. READ MORE

  5. 5. Glucose regulation and coronary artery disease : Studies on prevalence, recognition and prognostic implications

    Author : Malgorzata Zofia Bartnik; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Glucose metabolism; coronary artery disease; classification; prevalence; prognosis; risk oral glucose tolerance test; diabetes mellitus;

    Abstract : Coronary artery disease and diabetes mellitus type 2 represent chronic diseases of substantial and growing prevalence. Their coincidence is common, markedly enhancing mortality and morbidity. The risk for cardiovascular disease increases along a spectrum of blood glucose concentrations from levels regarded as normal. READ MORE