Search for dissertations about: "Orfs"

Showing result 1 - 5 of 21 swedish dissertations containing the word Orfs.

  2. 1. Methods and Applications in Comparative Bacterial Genomics

    Author : Hans-Henrik Fuxelius; Siv Andersson; Björn Andersson; Uppsala universitet; []
    Keywords : Biology; Biologi;

    Abstract : Comparative studies of bacterial genomes, now counting in the hundreds, generate massive amounts of information. In order to support a systematic and efficient approach to genomic analyses, a database driven system with graphic visualization of genomic properties was developed - GenComp. READ MORE

  4. 2. Strategies to explore the membrane proteome of a cell

    Author : Gianluca Maddalo; Leopold L. Ilag; Peter James; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Proteomics; Escherichia coli; Enterococcus faecalis; Synechocystis; Mass Spectrometry; BN SDS-PAGE; FT-ICR-MS; Myelin P2 protein; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : The cell envelope plays key roles in numerous processes such as maintaining cellular integrity, communication with other cells, signal transduction, maintenance of cellular homeostasis, and regulation of the traffic of molecules between the cell and the extracellular milieu. Essential membrane components in many of these processes are proteins. READ MORE

  5. 3. In silico analysis of pathways targeted by EBV infection and malignant transformation

    Author : Ramakrishna Rao Sompallae; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bioinformatics; systems biology; gene expression analysis; Epstein-Barr virus; Burkitt s lymphoma;

    Abstract : Epstein-Barr virus (EBV) is a ubiquitous γ-herpes virus with dual cell tropism for human B-lymphocytes and epithelial cells. EBV infection is linked to several malignancies such as Burkitt s lymphoma (BL) and nasopharyngeal carcinoma (NPC). READ MORE

  6. 4. Causes of Substitution Frequency Variation in Pathogenic Bacteria

    Author : Wagied Davids; Siv Andersson; Otto Berg; Bengt Persson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Comparative genomics; Molecular evolution; Bioinformatics; Human pathogens; Rickettsia; Helicobacter pylori; Biologi; Biology; Biologi;

    Abstract : Estimating substitution frequencies at sites that influence (Ka) and do not influence (Ks) the amino acid sequence is important for understanding the dynamics of molecular sequence evolution and the selective pressures that have shaped genetic variation. The aim of this work was to gain a deeper understanding of the driving forces of substitution frequency variation in human pathogens. READ MORE

  7. 5. The Role of Polyadenylation in Human Papillomavirus Type 16 Late Gene Expression

    Author : Daniel Öberg; Stefan Schwartz; Sheila Graham; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; HPV-16; polyadenylation; mRNA stability; codon usage; hnRNP H; DSE; splicing; negative element; RNA processing; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : High-risk type human papillomaviruses (HPVs) are associated with cancer. HPVs are strictly epitheliotropic and infect basal cell layers, establishing a life cycle strongly linked to the differentiation stage of the infected cells. The viral capsid late genes, L2 and L1, are only expressed in terminally differentiated epithelium. READ MORE