Search for dissertations about: "Organisk syntes"

Showing result 21 - 25 of 131 swedish dissertations containing the words Organisk syntes.

  2. 21. Synthesis and functionalization of ring-fused 2-pyridones : Targeting pili formation in E. coli

    Author : Nils Pemberton; Fredrik Almqvist; Oliver Kappe; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 2-pyridone; acylketene; antibacterial; biofilm inhibitor; Mannich; Micro-wave-assisted chemistry; peptidomimetic; virulence.; Organic synthesis; Organisk syntes;

    Abstract : Bicyclic dihydrothiazolo fused 2-pyridones have been studied as a new class of antibacterial agents, termed pilicides, that target the formation of adhesive bacterial surface organelles (pili) in pathogenic bacteria. Synthetic methods to further functionalize the bicyclic 2-pyridone scaffold have been developed in order to increase water-solubility and thereby facilitate biological evalua-tions. READ MORE

  4. 22. Molecular design, synthesis and performance evaluation of phenothiazine-based small molecules for efficient organic solar cells

    Author : Srikanth Revoju; Bertil Eliasson; Haining Tian; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic solar cell; small molecule donors; phenothiazine; power conversion efficiency; organisk kemi; Organic Chemistry;

    Abstract : Photovoltaics offers one of the most promising routes to generate electricity in a clean way. As an emerging technology in photovoltaics, organic solar cells (OSC) have attracted a great deal of attention owing to their potential low-cost, lightweight, flexibility and solution processability. READ MORE

  5. 23. Design, Synthesis and Thermodynamic Studies of Galectin Ligands

    Author : Maria Luisa Verteramo; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; galectin; conformational entropy; solvation; thermodynamic; interaction; molecular recognition; thiodigalactoside; diastereomer; structure-based design;

    Abstract : The signaling within and between cells in biology is governed by molecular recognition between natural or synthetic ligands and proteins. This thesis project aimed to investigate the thermodynamic properties of specific interaction between synthetic ligands and galectin proteins. READ MORE

  6. 24. Synthesis of Indole Alkaloids and Development of New Methodology

    Author : Anita Hoang; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; total synthesis; indole alkaloids; Domino reactions; vicinal quaternary stereocenters; quaternary stereocenter; indoline synthesis; communesin alkaloid; perophoramidine; dehaloperophoramidine; akuammiline alkaloids; strictamine; intramolecular Heck reaction; domino carbopalladation carbonylation; indoline alkaloids;

    Abstract : This thesis describes our efforts towards the total synthesis of natural products and the development of a newmethodology to afford a synthetically important scaffold.Chapter 2 outlines our efforts towards the total synthesis of a marine natural product, perophoramidine as wellas our completed synthesis of dehaloperophoramidine. READ MORE

  7. 25. Synthesis of Spiro-bicyclo[2.2.2]Octane Derivatives Towards the Development of Paclitaxel Mimetics

    Author : Viveca Thornqvist; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Kemi; Organic chemistry; Organisk kemi; Chemistry; Natural science; paclitaxel; spiro; indium; Naturvetenskap; bicyclo[2.2.2]octane; allylation; paclitaxel mimetic;

    Abstract : Many of the drugs that are developed in the pharmaceutical industry have their origin in natural products. Paclitaxel, the active substance of the medicine Taxol, was found in the bark of the Pacific yew tree (Taxus brevifolia). READ MORE