Search for dissertations about: "Organotypic cultures"

Showing result 11 - 15 of 29 swedish dissertations containing the words Organotypic cultures.

  2. 11. Investigations into the distribution and function of nucleobindin 1

    Author : Paul Williams; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The nucleobindin proteins (NUCB1 and NUCB2) are both characterised by DNA- and calcium-binding motifs. The functionality of these motifs has been demonstrated, but has not yet led to the identification of a role for either protein. READ MORE

  4. 12. The breathing brainstem : development of inspiration

    Author : David Forsberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Breathing is essential for life, and yet we do not fully understand the mechanisms that control it. The main central pattern generators for respiration include the inspiratory generating region called the preBötzinger Complex (preBötC), and the chemosensitive region called the parafacial respiratory group/retrotrapezoid nucleus (pFRG/RTN). READ MORE

  5. 13. Neural stem cell engraftment : functional interactions, brain repair and gap junctions

    Author : Johan Jäderstad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neural stem cell (NSC) engraftment therapies show increasing promise as potential cures for several of the diseases of the central nervous system. Traditionally, functional improvements after NSC engraftment have been attributed to replacement of lost neurons and astrocytes, remyelination and support of adjacent cells at risk. READ MORE

  6. 14. Retinoic Acid Metabolism Blocking Agents and the Skin : In vivo and in vitro Studies of the Effects on Normal and Diseased Human Epidermis

    Author : Elizabeth Pavez Loriè; Anders Vahlquist; Hans Törmä; Marie Virtanen; Helen Håkansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP; CYP26; retinoids; vitamin A; RAMBA; metabolism; keratinocyte; epidermis; retinoid regulated genes; Dermatology and venerology; Dermatologi och venerologi;

    Abstract : Retinoic Acid Metabolism Blocking Agents (RAMBAs) increase the endogenous levels of all-trans retinoic acid (RA) by inhibiting CYP26 enzymes. Thus they are believed to mimic the effects of retinoid treatment. Their mechanism of action and effects on vitamin A metabolism in keratinocytes are however uncertain. READ MORE

  7. 15. Dopamine neurons in ventral mesencephalon : interactions with glia and locus coeruleus

    Author : Elisabet Berglöf; Ingrid Strömberg; Stephen B. Dunnett; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; ventral mesencephalon; nerve fiber formation; glia; locus coeruleus; grafting; antioxidant-enriched diet; Histology; Histologi;

    Abstract : Parkinson’s disease is a progressive neurodegenerative disorder, characterized by a depletion of the dopaminergic neurons in the substantia nigra. The cause of the disease is yet unknown but age, oxidative stress, and neuroinflammation are some of the features involved in the degeneration. READ MORE